DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and MTG1

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_013815.1	Gene:	MTG1 / 855122	SGDID:	S000004703	Length:	367	Species:	Saccharomyces cerevisiae

Alignment Length:	269	Identity:	72/269 - (26%)
Similarity:	103/269 - (38%)	Gaps:	72/269 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   126 KYKNAVT--KEQSLKQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVL 188
            ||...:|  |...:|. .|.|.|::...::::|:.|.|.||.||....:|..|......:|| |.
Yeast    26 KYSMPLTDFKGHQVKA-LKTFEKLLPQMNMIIELRDIRAPLSTRNVVFDRIARKEHDVMKLV-VY 88

  Fly   189 NKADLVPRE-----NLNNWIKYFRRSGPVTAFKASTQDQANRLGRRKL--------REMKTEKAM 240
            .:.||:|..     .|.||.:....       |....|..|:...|.|        .|::|.
Yeast    89 TRKDLMPGNKPYIGKLKNWHEELGE-------KFILLDCRNKTDVRNLLKILEWQNYELETN--- 143

  Fly   241 QGSVCIGAELLMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSIINSL--------TRGRS----C 293
                           |.|     :....|..:.|:||||||::||||        ..||.    .
Yeast   144 ---------------GGY-----LPMGYRALITGMPNVGKSTLINSLRTIFHNQVNMGRKFKKVA 188

  Fly   294 MVGSTPGVTKSMQEV--------ELDSKIKLIDCPGIVFTSGGENSHAVLKNAQRVGDVK----D 346
            ..|:..|||::..||        |..::|.|||.||| ...|..:.|..:......|.||    |
Yeast   189 KTGAEAGVTRATSEVIRVTSRNTESRNEIYLIDTPGI-GVPGRVSDHNRMLGLALCGSVKNNLVD 252

  Fly   347 PFTIAESVL 355
            |...|:.:|
Yeast   253 PIFQADYLL 261

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	8/25 (32%)
		RbgA	121..443	CDD:224083	72/269 (27%)
		Nucleostemin_like	152..322	CDD:206753	53/202 (26%)
		Ras_like_GTPase	271..>400	CDD:206648	36/109 (33%)
MTG1	NP_013815.1	RbgA	18..367	CDD:224083	72/269 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810