DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and MRX8

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_010623.3	Gene:	MRX8 / 851936	SGDID:	S000002744	Length:	314	Species:	Saccharomyces cerevisiae

Alignment Length:	330	Identity:	80/330 - (24%)
Similarity:	123/330 - (37%)	Gaps:	81/330 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 EQSLKQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPREN 198
            ||..|:|.......|:|  :|...  .|..|.|:.: ||:|.:..|    ...:..|.:..|:|.
Yeast     2 EQLCKRYVHTPAAFIQN--IVANT--KRTTLATQLS-VEKAKKKVP----KTALKKKLNSRPKER 57

  Fly   199 LNNWIK--------YFRRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSV----CIGAELL 251
            |.||:|        |.:.|.       |..::.||...:...|.:...|....:    .:..:..
Yeast    58 LPNWLKLNDVFNIHYEKPSN-------SDINKVNRFFNKAKVEFEWCAASFDDIPENPFLNKKSH 115

  Fly   252 MSMLGNY--CRNKGIKTSIRVGVVGIPNVGKSSIINSLTR-------GRSCMVGSTPGVTKSMQE 307
            ..:|.::  |....|.|...|..:|..|||||||:|::|.       |....|..|.|.||::..
Yeast   116 KDILKDHGECGTTLIDTLPEVIFLGGTNVGKSSILNNITTSHVSRDLGSLARVSKTTGFTKTLNC 180

  Fly   308 VELDSKIKLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESVLKRASKEYFCTMY----- 367
            ..:.:::::||.||..|.|..|.....|:           :.:....|.|      |.:.
Yeast   181 YNVGNRLRMIDSPGYGFNSSKEQGKVTLQ-----------YLLERKQLVR------CFLLLAGDK 228

  Fly   368 DITNYDT------------FEEFFAK--KAARMGKFLKK----GVPDVVAAARSVLNDWNTGKIK 414
            :|.|.|.            ||..|.|  |...:.||.||    |:.|:....|.||    |..:.
Yeast   229 EINNTDNMIIQYIHEHGVPFEVVFTKMDKVKDLNKFKKKVMSSGLMDLPTLPRLVL----TNSLT 289

  Fly   415 YCTQP 419
            ..|.|
Yeast   290 SSTSP 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	5/15 (33%)
		RbgA	121..443	CDD:224083	80/330 (24%)
		Nucleostemin_like	152..322	CDD:206753	46/190 (24%)
		Ras_like_GTPase	271..>400	CDD:206648	41/158 (26%)
MRX8	NP_010623.3	EngB	86..314	CDD:223296	54/230 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000