DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Ns1 and Noa1

DIOPT Version :9

Sequence 1:NP_732199.2 Gene:Ns1 / 42060 FlyBaseID:FBgn0038473 Length:581 Species:Drosophila melanogaster
Sequence 2:NP_062810.1 Gene:Noa1 / 56412 MGIID:1914306 Length:693 Species:Mus musculus


Alignment Length:419 Identity:84/419 - (20%)
Similarity:142/419 - (33%) Gaps:155/419 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    64 LKEVEEAKQRQEAERLARREAFKAEREQNK----FKTLESMVEDADMRSTVHGI----------- 113
            |:|:::.:|.:|.|||.:||    ||.|.|    |:|| .:.|..|......||           
Mouse    92 LRELQQLQQEKERERLQQRE----ERLQQKLRAGFRTL-PVPEFPDASVPPSGIYCSGCGAELHC 151

  Fly   114 MHENDAQDQDEKKYKNA----------------------------VTKEQSLKQYFKEFRKVIEN 150
            .|........|:|:::|                            |:::|.|:......|:  ..
Mouse   152 QHPGLPGYLPEEKFRDAAQAEGGPARTVCQRCWLLVHHGRALRLQVSRDQYLELVSAALRR--PG 214

  Fly   151 ADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYFR-------- 207
            ..:||.:|:..|.......::.:.|    |.|:|:::.||.||:| ::...::|..|        
Mouse   215 PALVLYMVNLLDLPDALLPDLPKLV----GPKQLIVLGNKVDLLP-QDAPGYLKRLRKRLWDDCI 274

  Fly   208 RSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSVCI-------------GAELLMSMLGNYC 259
            |:|.|.|  ...|......|...|.|:|.:.....|..:             |.|.::|.|....
Mouse   275 RAGLVVA--PGHQGPQYPAGDEPLEEIKNQNPSSRSRTVVKDVRLISAKTGYGVEEMISALQRSW 337

  Fly   260 RNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSC-----------MVGSTPG------------- 300
            |.:|     .|.:||..|.|||::.|:|.....|           .:...||             
Mouse   338 RYRG-----DVYLVGTTNAGKSTLFNTLLESDYCTAKGSEAIDRATISPWPGTTLNLLKFPICNP 397

  Fly   301 ---------------VTKSMQEVELDSKIKL-----------------------------IDCPG 321
                           .||:.:::..:.:.:|                             .|...
Mouse   398 TPYRMFKRQRRLQEDATKAEEDLSEEEQSQLNQLKKHGYIVGRVGRTFSYSREQDEVPFEFDADS 462

  Fly   322 IVFTSGGENSHAVLKNAQRV----GDVKD 346
            :.|..|.|...:|.|:.:::    .||||
Mouse   463 LAFDMGSEPVVSVCKSTKQIELTPEDVKD 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Ns1NP_732199.2 GN3L_Grn1 17..88 CDD:285863 9/23 (39%)
SurA_N_3 59..>150 CDD:304439 28/128 (22%)
RbgA 121..443 CDD:224083 63/347 (18%)
Nucleostemin_like 152..322 CDD:206753 47/258 (18%)
Ras_like_GTPase 271..>400 CDD:206648 24/148 (16%)
Noa1NP_062810.1 TMEM247 <33..>129 CDD:292084 16/41 (39%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 43..67
Med21 <79..120 CDD:288119 13/31 (42%)
PRK13796 140..655 CDD:237511 65/366 (18%)
YqeH 180..396 CDD:206748 47/229 (21%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 286..307 4/20 (20%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1161
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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