Protein Alignment Ns1 and Ns2

DIOPT Version :9

• Sequence 1: NP_732199.2
• Gene: Ns1 / 42060
• FlyBaseID: FBgn0038473
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_611232.1
• Gene: Ns2 / 36989
• FlyBaseID: FBgn0034243
• Length: 674
• Species: Drosophila melanogaster
• Alignment Length: 636
• Identity: 180/636 - (28%)
• Similarity: 280/636 - (44%)
• Gaps: 111/636 - (17%)

  Fly     3 LKRL---KTKKSKR------LT-----GRLKHKIEKKVRDHNKKERRAAKKNPKKGSKKQKLIQI 53
            :|||   :..|:||      ||     |||......:|           :..||..|..:.:.|.
  Fly    44 IKRLQMYRNFKAKRDRTGKILTPAPFQGRLPAGTMARV-----------EPTPKWFSNSRVISQT 97

  Fly    54 PNICPFKDDILKEVEEAKQ------------RQEAERLAR-----REAF--------KAEREQNK 93
            . :..|:|:|.|.|::..|            ..||.:..|     .|:|        :.:|...|
  Fly    98 A-LQKFQDEIGKAVKDPYQVIMKPSQLPVTLLNEAAKYKRVHLLDTESFDSTFGPKKQRKRVSLK 161

  Fly    94 FKTLESMVEDADMRSTVHGIMHEND--AQDQDEKK-YKNAVTKEQSLKQYFKEFRKVIENADVVL 155
            .:.||.:.:.||.::..:....:.|  .:|..||| .::.|......|:.:.|..||::.:||:|
  Fly   162 VRDLEDLSKAADDQADKYDSAKDLDLIREDTGEKKAVRDWVFGAGQSKRIWNELHKVVDASDVLL 226

  Fly   156 EVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYFRRSGPVTAFKASTQ 220
            :|:|||||:|||...:|..:|....:|.|..:|||.||||......|:.......|..||.||.|
  Fly   227 QVLDARDPMGTRSKYIEEFLRKEKPHKHLFFILNKVDLVPVWVTQRWVAILSAEYPTIAFHASLQ 291

  Fly   221 DQANRLGRRKLREMKTEKAMQGSVCIGAEL-LMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSII 284
            ....:                     ||.: |...||....:   |..|.||.:|.|||||||:|
  Fly   292 HPFGK---------------------GALINLFRQLGKLHLD---KKQISVGFIGYPNVGKSSVI 332

  Fly   285 NSLTRGRSCMVGSTPGVTKSMQEVELDSKIKLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFT 349
            |:|...:.|.|....|.||..|.:.|..:|.||||||:|:.:...::..|||...||..|.:|..
  Fly   333 NALRSKKVCKVAPIAGETKVWQYITLMKRIFLIDCPGVVYPTAETDTEKVLKGVVRVELVTNPED 397

  Fly   350 IAESVLKRASKEYFCTMYDITNYDTFEEFFAKKAARMGKFLKKGVPDVVAAARSVLNDWNTGKIK 414
            ..:|:|||...||....|.|.:::|...|..:.|.:.||.||.|.|||...||.|||||..||:.
  Fly   398 YVDSLLKRVRPEYISKNYKIEHWNTSTHFLEQLAQKTGKLLKGGEPDVTVTARMVLNDWQRGKLP 462

  Fly   415 YCTQP-----PEVQEGQSVHISASIVHSEAREFDVENFESMETEILEHCAVKTDDIMEITSTGPL 474
            :...|     |:.|||:...:.|...:.:|:. :...|.|...:       |..:..:|.....:
  Fly   463 FYVPPEGFAVPKSQEGKEEEVVAEDPNEDAKS-EAPTFVSESVK-------KAREFKQIQDFRKI 519

  Fly   475 EI--RQPREEAEPADKITASLVIDEKEKPAKGRKRKL----DEEKEKVDPSLLL----EENQSLN 529
            .:  ...:|:.:..|.|...|:..:|.:.|..:|.::    :|::|..|.:...    |.|:.|.
  Fly   520 RVGLEYEQEDVKDLDHIDLELLEQQKAERAAKKKARIHNLGEEDEESSDGADEFYSEDEYNEDLQ 584

  Fly   530 KGIKQMQKLKKKQNV----RNEKKISKI-----TDVLDSFSLGPSSSKAEK 571
            :.:.:..|.||.|.:    ..:.:::||     .....|...|||:|||.:
  Fly   585 RVVHKKAKSKKPQQLAITSSGKFRVAKIQPGDSDGAGSSDDDGPSTSKAPR 635

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863	18/95 (19%)
		SurA_N_3	59..>150	CDD:304439	27/118 (23%)
		RbgA	121..443	CDD:224083	116/328 (35%)
		Nucleostemin_like	152..322	CDD:206753	63/170 (37%)
		Ras_like_GTPase	271..>400	CDD:206648	53/128 (41%)
Ns2	NP_611232.1	NGP1NT	50..179	CDD:285379	30/140 (21%)
		RbgA	206..485	CDD:224083	109/302 (36%)
		NGP_1	214..370	CDD:206751	66/179 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435337
Domainoid	1	1.000	42	1.000	Domainoid score	I753
eggNOG	1	0.900	-	-		E1_COG1161
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1210675at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11089
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850