Protein Alignment Ns1 and Ns4

DIOPT Version :9

• Sequence 1: NP_732199.2
• Gene: Ns1 / 42060
• FlyBaseID: FBgn0038473
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: NP_610055.1
• Gene: Ns4 / 35338
• FlyBaseID: FBgn0032882
• Length: 575
• Species: Drosophila melanogaster
• Alignment Length: 588
• Identity: 130/588 - (22%)
• Similarity: 218/588 - (37%)
• Gaps: 170/588 - (28%)

  Fly     7 KTKKSKRLTGRLKHKIEKKVR---------DHNKKERRAAKKNPKKGSKKQKLIQIPNICPFKDD 62
            |.||.:.|..|......|.:|         |..:..|:..::...:|..:.|.:...|: .|..:
  Fly    13 KKKKDQMLQKRNTKGPPKYLRSTQESYEDSDVPETTRKLMEQPFARGGNRNKNVNRYNL-QFYQE 76

  Fly    63 ILKEVEEAKQRQEAERLARREAFK-------AERE-QNKF-----------KTLESMVEDADMRS 108
            ..||:|:.||          |.||       |:|| .:::           .||....|:.|...
  Fly    77 GKKELEQMKQ----------EGFKPFEKLSPAQREVDDRYFAGCDFPVRPPWTLTESKEELDRTE 131

  Fly   109 TVHGIMHENDAQDQDEKKYKNAVTKEQSL----KQYFKEFRKVIENADVVLEVVDARDPLGTRCN 169
            .    .:..:..|:.:||.:...:||.||    .:.:::..:|:|.:|::|.:||.|
  Fly   132 N----RYFKEYVDELQKKQRAGDSKELSLFELNLETWRQLWRVLEFSDILLIIVDVR-------- 184

  Fly   170 EVERAVRGAPG---------NKRLVLVLNKADLVPRENLNNWIKYFR---RSGPVTAF------- 215
              ...:...|.         .|..::|.||.|||....:..|.:|||   ...||..|
  Fly   185 --YATLMFPPSLYDYIINTLKKHAIVVFNKVDLVEPHAVVAWRQYFRDRYPQLPVVLFASFLPRS 247

  Fly   216 -KASTQ-DQANRLG------------------------RRKLRE-MKTEK---------AMQGSV 244
             |.|.: .||:|..                        .:|:|| |::::         |::|.:
  Fly   248 RKGSQRGPQAHRRSMEGVYNIYKECQRYVQGEVDLTTWEQKIREDMRSDQLDILDEISTAVEGEL 312

  Fly   245 CIGAELLMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVE 309
            .|.:.:..:...:...:.|:.|   :|.:|.|||||||:||:|...:...|..|||.||..|.:.
  Fly   313 KISSSIDTTPHEHVKYHSGVLT---IGCIGFPNVGKSSLINALKGRKVVSVSRTPGHTKHFQTIF 374

  Fly   310 LDSKIKLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESVLKRASKEYFCTMYDITNYDT 374
            |...::|.||||:||.|....|..||..:..:..:..|:...:.:.:..:......::...:||.
  Fly   375 LTPLVRLCDCPGLVFPSSTPKSLQVLLGSFPISQLAVPYRSLKFLGEHLNLPQLLRLHLPEDYDE 439

  Fly   375 FEE------------FFAKKAARMGKFLKKGVPDVVAAARSVL---------------------- 405
            :..            |...||||         ||...||..:|
  Fly   440 WSAVAISDAWAYKRGFLTAKAAR---------PDRYRAANHILRMCLAGQQMLVLQFYPPGFEER 495

  Fly   406 -NDW----NTGKIKYCTQ-----PPEVQEGQSVHISASIVHSEAREFDVENFESMETEILEHCAV 460
             ..|    :.|::|...|     |.....|.:..:.:....||..:.|..|.|:...|  |.|.:
  Fly   496 REHWLQHPDVGEVKKYQQVELDEPESETNGDTSSVCSDTADSEDEDEDSSNDETNADE--EECGI 558

  Fly   461 KTD 463
            :.|
  Fly   559 RED 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863	17/86 (20%)
		SurA_N_3	59..>150	CDD:304439	24/113 (21%)
		RbgA	121..443	CDD:224083	95/424 (22%)
		Nucleostemin_like	152..322	CDD:206753	58/224 (26%)
		Ras_like_GTPase	271..>400	CDD:206648	41/140 (29%)
Ns4	NP_610055.1	HSR1_MMR1	163..390	CDD:206750	62/239 (26%)
		GTPase_YlqF	165..474	CDD:274669	79/330 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45435331
Domainoid	1	1.000	42	1.000	Domainoid score	I753
eggNOG	1	0.900	-	-		E1_COG1161
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.740