DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and Mtg1

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	NP_955005.2	Gene:	Mtg1 / 212508	MGIID:	2685015	Length:	326	Species:	Mus musculus

Alignment Length:	314	Identity:	78/314 - (24%)
Similarity:	127/314 - (40%)	Gaps:	85/314 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   142 KEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNKADLVPRENLNNWIKYF 206
            |:.:..:::.|.|:||.|||.|...| |.:.:.:.|.   |..:|||||.||
Mouse    39 KKMQSSLKSVDCVIEVHDARIPFSGR-NPLFQELLGL---KPHLLVLNKMDL------------- 86

  Fly   207 RRSGPVTAFKASTQDQANRLGRRKLREMKTEKAMQGSV---CIGAELLMSMLG--------NYCR 260
                            |:...::|:.:...||.:...:   |:..|.:..::.        :|..
Mouse    87 ----------------ADLTEQQKIVQRLEEKGLSNVLFTNCVKDENIKQIVPKVMELIRCSYRY 135

  Fly   261 NKGIKTSIRVGVVGIPNVGKSSIINSLTR-----GRSCMVGSTPGVTKSM-QEVELDSK--IKLI 317
            ::.......:.|||:|||||||:||||.|     |::..||..||:|::: ..:::..:  :.|:
Mouse   136 HRAETPEYCIMVVGVPNVGKSSLINSLRRQHLRTGKAARVGGEPGITRAVTSRIQVCERPLVFLL 200

  Fly   318 DCPGIVFTSGGENSHAVLKNAQRVGDVKDPF----TIAESVLKRASKEYFCTMYDITNY------ 372
            |.|| |.....|:....||.| ..|.|.|..    |:|:.:|      |....:.:..|
Mouse   201 DTPG-VLAPRIESVETGLKLA-LCGTVLDHLVGEETMADYLL------YTLNRHGLFGYVQHYAL 257

  Fly   373 ----DTFEEFFAKKAARMGKFLKKGV-----------PDVVAAARSVLNDWNTG 411
                |..|......|.::.|..|..|           ||...|||..|..:.:|
Mouse   258 ASACDQIEWVLKNVAIKLRKTRKVKVLTGTGNVNVIQPDYAMAARDFLRTFRSG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	1/7 (14%)
		RbgA	121..443	CDD:224083	78/314 (25%)
		Nucleostemin_like	152..322	CDD:206753	50/188 (27%)
		Ras_like_GTPase	271..>400	CDD:206648	46/161 (29%)
Mtg1	NP_955005.2	GTPase_YlqF	29..319	CDD:274669	78/314 (25%)
Mtg1	NP_955005.2	YlqF	29..206	CDD:206749	52/200 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810