Protein Alignment Ns1 and Gnl1

DIOPT Version :9

• Sequence 1: NP_732199.2
• Gene: Ns1 / 42060
• FlyBaseID: FBgn0038473
• Length: 581
• Species: Drosophila melanogaster
• Sequence 2: XP_036016217.1
• Gene: Gnl1 / 14670
• MGIID: 95764
• Length: 730
• Species: Mus musculus
• Alignment Length: 579
• Identity: 133/579 - (22%)
• Similarity: 223/579 - (38%)
• Gaps: 133/579 - (22%)

  Fly     3 LKRLKTKKSKRL------TGRLKHKIEKKVRDHNKKERRAAKKNPKKGSKKQKLIQIPNICPFKD 61
            ::||..:.|:.|      ..|.:...|:..|:..::.:|||         :::::|     |...
Mouse   183 IRRLNQQPSQGLGPRGYDPNRYRLHFERDSREEVERRKRAA---------REQVLQ-----PVSA 233

  Fly    62 DILK-EVEEAKQRQEAERLARREAFKAEREQNKFKTLESMVEDADMRSTVHGIMHENDAQDQDEK 125
            ::|: ::.|..|........||..:..|..:.:..:.|.. ...:....:||      |...::.
Mouse   234 EVLELDIREVYQPGSVLDFPRRPPWSYEMSKEQLMSQEER-SFQEYLGKIHG------AYTSEKL 291

  Fly   126 KYKNAVTKEQSLKQYFKEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNK 190
            .|     .|.:|:.: ::..:|:|.:|:||.:.|.|.|:......:...|.|..| ..|||||||
Mouse   292 SY-----FEHNLETW-RQLWRVLEMSDIVLLITDIRHPVVNFPPALYEYVTGELG-LALVLVLNK 349

  Fly   191 ADLVPRENLNNWIKYFRRSGP------VTAFKASTQ---------DQANRLGRRKLREMKTEKAM 240
            .||.|...:..|..||.:..|      .|:|...|:         .:..|.|:...|.:..|:.:
Mouse   350 VDLAPPALVVAWKHYFHQCYPQLHIVLFTSFPRDTRTPQEPGGVLKKNRRRGKGWTRALGPEQLL 414

  Fly   241 QG--SVCIGAELLMSMLGNYCRN------------------------------------------ 261
            :.  ::.:|...|.|......|:
Mouse   415 RACEAITVGKVDLSSWREKIARDVAGASWGNVSGEEEEEEDGPAVLVEQLTDSAMEPTGPSRERY 479

  Fly   262 -KGIKTSIRVGVVGIPNVGKSSIINSLTRGRSCMVGSTPGVTKSMQEVELDSKIKLIDCPGIVFT 325
             .|:.|   :|.:|.|||||||:||.|...:...|..|||.|:..|...|...:||.||||::|.
Mouse   480 KDGVVT---IGCIGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFP 541

  Fly   326 SGGENSHAVLKNAQRVGDVKDPFT----IAESVLKRA------------SKEYFCTMYDITNYDT 374
            |.......||.....:..:::|:|    :|..:..:|            |.|:....:||.
Mouse   542 SLLPRQLQVLAGIYPIAQIQEPYTSVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDIC---- 602

  Fly   375 FEEFFAKKAARMGKFLKKGVPDVVAAARSVLNDWNTGKIKYCTQPPEVQEGQSVHIS----ASIV 435
              |.:|:|  |..|..|....||..||.|:|.....|::..|..||...|.:....|    |.:|
Mouse   603 --EAWAEK--RGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFYPPGYSEQRGTWESHPETAELV 663

  Fly   436 HSEAR---EFDVENFESMETEILEHCAVKTDDIMEITSTGPLEIRQPREEAEPADKITA 491
            .|:.|   ..|.|  |..|.|:...|..:.::..:....|  |..:....::|...:||
Mouse   664 LSQGRVGPAGDEE--EEEEEELSSSCEEEGEEDRDADEEG--EGDEDTPTSDPGSCLTA 718

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863	13/71 (18%)
		SurA_N_3	59..>150	CDD:304439	14/91 (15%)
		RbgA	121..443	CDD:224083	100/404 (25%)
		Nucleostemin_like	152..322	CDD:206753	60/229 (26%)
		Ras_like_GTPase	271..>400	CDD:206648	45/144 (31%)
Gnl1	XP_036016217.1	RbgA	293..637	CDD:224083	91/361 (25%)
		HSR1_MMR1	300..541	CDD:206750	63/245 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810