DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ns1 and mtg1

DIOPT Version :9

Sequence 1:	NP_732199.2	Gene:	Ns1 / 42060	FlyBaseID:	FBgn0038473	Length:	581	Species:	Drosophila melanogaster
Sequence 2:	XP_021336162.1	Gene:	mtg1 / 100150980	ZFINID:	ZDB-GENE-031110-2	Length:	319	Species:	Danio rerio

Alignment Length:	322	Identity:	80/322 - (24%)
Similarity:	131/322 - (40%)	Gaps:	71/322 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   134 EQSLKQYF--------KEFRKVIENADVVLEVVDARDPLGTRCNEVERAVRGAPGNKRLVLVLNK 190
            |:.:..:|        |:.|..:.|.|.::|:.|||.|...|.:..:.::...|.    :|||||
Zfish    21 ERDVTHWFPRHMAKGLKQMRANLRNVDCIIEIHDARIPFSGRNSSFQESLDVRPH----LLVLNK 81

  Fly   191 ADLVPRENLNNWIKYFRRSGPVTAFKASTQDQANRLGRR------KLREMKTEKAMQGSVCIGAE 249
            .|:.......:.:|.|.|.|...........|.:...::      ||.|..:....:...|
Zfish    82 MDVADISKKQSILKQFEREGVKNVLFTDCLRQHDENVKKIVPLVSKLIESTSRFHREEERC---- 142

  Fly   250 LLMSMLGNYCRNKGIKTSIRVGVVGIPNVGKSSIINSLTR-----GRSCMVGSTPGVTKS-MQEV 308
                    ||          :.|:|:|||||||:||:|.|     |::..||:.||:||: :.::
Zfish   143 --------YC----------LMVIGVPNVGKSSLINALRRTYLKKGKASKVGAEPGITKAVLTKI 189

  Fly   309 ELDSK--IKLIDCPGIVFTSGGENSHAVLKNAQRVGDVKDPFTIAESV--------LKRASKEYF 363
            ::..:  |.|:|.|| |.....||....:|.| ..|.|.| ..:.|.|        |.|..:..:
Zfish   190 QVCERPIIHLLDTPG-VLPPRIENIETGMKLA-LCGTVLD-HLVGEDVIADFLLFSLNRLERFSY 251

  Fly   364 CTMYDITN-YDTFEEFFAKKAARMGKFLK----KGV-------PDVVAAARSVLNDWNTGKI 413
            ...|.:.. .|..:......|.::||..:    .||       ||..|||...:..:..|::
Zfish   252 VEKYSLEEPCDDIQHVLKCIAVKLGKTRRVKAITGVGNITVQLPDYSAAAYDFIRAFRKGEL 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ns1	NP_732199.2	GN3L_Grn1	17..88	CDD:285863
		SurA_N_3	59..>150	CDD:304439	4/23 (17%)
		RbgA	121..443	CDD:224083	80/322 (25%)
		Nucleostemin_like	152..322	CDD:206753	49/183 (27%)
		Ras_like_GTPase	271..>400	CDD:206648	46/156 (29%)
mtg1	XP_021336162.1	RbgA	26..319	CDD:331156	79/317 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1161
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810