Protein Alignment Dad and Smox

DIOPT Version :10

• Sequence 1: NP_001369021.1
• Gene: Dad / 42059
• FlyBaseID: FBgn0020493
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_511079.1
• Gene: Smox / 31738
• FlyBaseID: FBgn0025800
• Length: 486
• Species: Drosophila melanogaster
• Alignment Length: 473
• Identity: 116/473 - (24%)
• Similarity: 182/473 - (38%)
• Gaps: 157/473 - (33%)

  Fly   214 GKRFREDFEALMKQLKRKQRNELLLAVKSRLDPPTKTQRDVVEPTTTTAPTYLQCILIP-CKTQT 277
            ||...:..:.|:|::|:                  .:|.:.:|...:|.....:|:.:| .|...
  Fly    26 GKWSEKAVKNLVKKIKK------------------NSQLEELERAISTQNCQTRCVTVPRSKPAP 72

  Fly   278 VWE------PHVTASRLFFWRELWNAKELKRLPTCPAA----RDCIYMCCNPLHWFRI---LHQP 329
            ..|      |||...||:.|.:|.:..|||.|..|..|    ::.|  |.||.|:.:|   :..|
  Fly    73 AGEHLRKGLPHVIYCRLWRWPDLQSQNELKPLDHCEYAFHLRKEEI--CINPYHYKKIELSILVP 135

  Fly   330 ETESPTPPYQRSKMLRLKDA--DFEEDSQ----------NDA--KSAAL---------------- 364
            :: .||||          |:  |:..|:.          |.|  :||:|
  Fly   136 KS-LPTPP----------DSIVDYPLDNHTHQIPNNTDYNAAIIRSASLSPPQYMELGGAGPVSV 189

  Fly   365 ------------------STWSAESTSISNIYK-------------------------------P 380
                              |:.|:.|:|.::.|:                               |
  Fly   190 SSSASSTPATAAGGGGGPSSSSSSSSSAASAYQQQQQQLSFGQNMDSQSSVLSVGSSIPNTGTPP 254

  Fly   381 ALYESVTTDGKDHNINSQV-------------------WCQIAYWEMAHRVGEFFHAKTNAVNI- 425
            ..|.|...|..|.|.|..:                   ||.|:|:|:..||||.|||...::.:
  Fly   255 PGYMSEDGDPIDPNDNMNMSRLTPPADAAPVMYHEPAFWCSISYYELNTRVGETFHASQPSITVD 319

  Fly   426 -YTDGIVASEVDSMCLRDLTPAGNQIHSVVPKARHTVGLGVTLSLENGDVWIYNRGNTTIFVDSP 489
             :||   .|..:..||..|:....  :.||.:.|..:|.||.|....|:|:.....:::|||.||
  Fly   320 GFTD---PSNSERFCLGLLSNVNR--NEVVEQTRRHIGKGVRLYYIGGEVFAECLSDSSIFVQSP 379

  Fly   490 TLSENLD----RVCKVMPGYCLKAFETNR-AELLSMR-DHGHHPMGPVDYF-SIKISFGKGWGRD 547
            ..::...    .|||:.||..||.|.... |.|||.. ..|...:..:... :|::||.||||.:
  Fly   380 NCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLSQSVSQGFEAVYQLTRMCTIRMSFVKGWGAE 444

  Fly   548 YKRQDIMGCPCWLEVHFS 565
            |:||.:...|||:|:|.:
  Fly   445 YRRQTVTSTPCWIELHLN 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dad	NP_001369021.1	MH1_SMAD_6_7	197..329	CDD:199813	31/128 (24%)
		MH2_I-SMAD	400..565	CDD:199821	60/173 (35%)
Smox	NP_511079.1	MH1_R-SMAD	7..130	CDD:199812	31/123 (25%)
		MH2_SMAD_2_3	285..475	CDD:199826	60/183 (33%)