Protein Alignment Dad and Smad1

DIOPT Version :9

• Sequence 1: NP_001369021.1
• Gene: Dad / 42059
• FlyBaseID: FBgn0020493
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: XP_006255456.1
• Gene: Smad1 / 25671
• RGDID: 3030
• Length: 483
• Species: Rattus norvegicus
• Alignment Length: 477
• Identity: 114/477 - (23%)
• Similarity: 186/477 - (38%)
• Gaps: 150/477 - (31%)

  Fly   222 EALMKQLKRKQRNELLLAVKSRLDPPTKTQRDVVEPTTTTAPTYLQCILIPCKTQTVWE------ 280
            :||:|:||:|         |..::...|......:|:        .|:.||.......:
  Rat    35 DALVKKLKKK---------KGAMEELEKALSCPGQPS--------NCVTIPRSLDGRLQVSHRKG 82

  Fly   281 -PHVTASRLFFWRELWNAKELKRLPTC--PAARDCIYMCCNPLHWFRILHQPETESPT-PPY--- 338
             |||...|::.|.:|.:..|||.|..|  |.......:|.||.|:.|:      |||. ||.
  Rat    83 LPHVIYCRVWRWPDLQSHHELKPLECCEFPFGSKQKEVCINPYHYKRV------ESPVLPPVLVP 141

  Fly   339 -------QRSKMLRLK-----------DADFEEDSQN---------------DAKSAALSTWSAE 370
                   |.|.:.:.:           :|.|.:..|.               ::..::.||:...
  Rat   142 RHSEYNPQHSLLAQFRNLGQNEPHMPLNATFPDSFQQPHSHPFPQSPNSSYPNSPGSSSSTYPHS 206

  Fly   371 STS------------------------------------ISNIYKPALYESVTTDGK-------D 392
            .||                                    ::|:..|.|...:...|:       :
  Rat   207 PTSSDPGSPFQMPADTPPPAYLPPEDPMAQDGSQPMDTNMTNMTAPTLPAEINRGGEVSCRSPCE 271

  Fly   393 HNINSQV----------WCQIAYWEMAHRVGEFFHAKTNAVNI--YTDGIVASEVDSMCLRDLTP 445
            ..:::.|          ||.|.|:|:.:||||.|||.:.:|.:  :||  .::..:..||..|:.
  Rat   272 SLLSADVQAVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD--PSNNKNRFCLGLLSN 334

  Fly   446 AGNQIHSVVPKARHTVGLGVTLSLENGDVWIYNRGNTTIFVDS----------PTLSENLDRVCK 500
            ...  :|.:...|..:|.||.|....|:|:.....:::|||.|          ||      .|||
  Rat   335 VNR--NSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPT------TVCK 391

  Fly   501 VMPGYCLKAFETNR-AELLSMR-DHGHHPMGPVDYF-SIKISFGKGWGRDYKRQDIMGCPCWLEV 562
            :..|..||.|.... |:||:.. :||...:..:... :|::||.||||.:|.|||:...|||:|:
  Rat   392 IPSGCSLKIFNNQEFAQLLAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEI 456

  Fly   563 HFSHLRXQYL--MLARSAGPHS 582
            |. |.. |:|  :|.:...||:
  Rat   457 HL-HGPLQWLDKVLTQMGSPHN 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dad	NP_001369021.1	MH1_SMAD_6_7	197..329	CDD:199813	29/115 (25%)
		MH2_I-SMAD	400..565	CDD:199821	60/179 (34%)
Smad1	XP_006255456.1	MH1_SMAD_1_5_9	9..132	CDD:199814	29/119 (24%)
		PRK10263	<133..>244	CDD:236669	12/110 (11%)
		MH2_SMAD_1_5_9	283..483	CDD:199822	66/206 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810