Protein Alignment Dad and daf-3

DIOPT Version :9

• Sequence 1: NP_001369021.1
• Gene: Dad / 42059
• FlyBaseID: FBgn0020493
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001300341.1
• Gene: daf-3 / 180431
• WormBaseID: WBGene00000899
• Length: 895
• Species: Caenorhabditis elegans
• Alignment Length: 603
• Identity: 131/603 - (21%)
• Similarity: 192/603 - (31%)
• Gaps: 211/603 - (34%)

  Fly    19 PSNGVSAAPPAQPPRPPPPPHRP---RPHQCTPSFGYSCNEEDSLAMRQTP-LPPYSSIACGMD- 78
            ||.|.:.|.|.    |...||.|   .|:...|...|..|......|.|.| :||......||:
 Worm   407 PSVGATFAHPL----PHQAPHNPGVSHPYSIAPQTHYPLNMNPIPQMPQMPQMPPPLHQGYGMNG 467

  Fly    79 --CSSSNSSSCGQSLSLSQGQGHNNNNSHPYRRLPNHMDVLPPPPSACDRCCTAPGYSCASSCDD 141
              |||.|::...|:       .|.|:.||     |||.                 .|.|..:...
 Worm   468 PSCSSENNNPFHQN-------HHYNDISH-----PNHY-----------------SYDCGPNLYG 503

  Fly   142 MLIDGSDL-----DQDRSPDQGQVQPVDRRMISATTFTTMFRKCCGGATESTSGSTLTIPVSTSR 201
            ......|.     .|...|.|          :|..                          .||:
 Worm   504 FPTPYPDFHHPFNQQPHQPPQ----------LSQN--------------------------HTSQ 532

  Fly   202 ATAHPP--QTQAQNGKRFREDFEALMKQLKRKQRNELLLAVKSRLDPPTKTQRDVVEPTTTTAPT 264
            ..:|.|  |.|..|                               |||  ..|.|::|:|.|...
 Worm   533 QGSHQPGHQGQVPN-------------------------------DPP--ISRPVLQPSTVTLDV 564

  Fly   265 YLQCILIPCKTQTVWEPHVTASRLFFWRELWNAKELKRLPTCPAARDCIYMCCNPLHWFRILHQP 329
            :.:.    |:.        |....||..|...:..:.|     ::...|....:|:....::..
 Worm   565 FRRY----CRQ--------TFGNRFFEGESEQSGAIIR-----SSNKFIEEFDSPICGVTVVRP- 611

  Fly   330 ETESPTPPYQRSKMLRLKDAD-FEEDSQNDAKSAALSTWSAESTSISNIYKPALYESVTTDGKDH 393
                           |:.|.: .|.....||....:..:....||          ||||..|:..
 Worm   612 ---------------RMTDGEVLENIMPEDAPYHDICKFILRLTS----------ESVTFSGEGP 651

  Fly   394 NIN--SQVWCQIAYWEMAHRVGEFFHAKTNAVNIYTD-GIVASEVDSMCLRDLTPAGNQIHSVVP 455
            .::  ::.|..|.|:|...::||   .|.:..|.:.| |.:.||  :.....|.|  |.|...|.
 Worm   652 EVSDLNEKWGTIVYYEKNLQIGE---KKCSRGNFHVDGGFICSE--NRYSLGLEP--NPIREPVA 709

  Fly   456 -KARHTVGLGVTLSL-ENGDVWIYNRGNTTIFVDSPTLSE-----NLDRVCKVMPGYCLKAFETN 513
             |.|..:..|:..|. ::|.||:.||....:||.|..|.|     ..|:|.||.....:|.|..|
 Worm   710 FKVRKAIVDGIRFSYKKDGSVWLQNRMKYPVFVTSGYLDEQSGGLKKDKVHKVYGCASIKTFGFN 774

  Fly   514 ------RAELLSMRDHGHHPMG---PVDYF------------------------SIKISFGKGWG 545
                  |..|||.:....:..|   |::|.                        .:::||.||:|
 Worm   775 VSKQIIRDALLSKQMATMYLQGKLTPMNYIYEKKTQEELRREATRTTDSLAKYCCVRVSFCKGFG 839

  Fly   546 RDY-KRQDIMGCPCWLEV 562
            ..| :|..|..||.|:|:
 Worm   840 EAYPERPSIHDCPVWIEL 857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dad	NP_001369021.1	MH1_SMAD_6_7	197..329	CDD:199813	23/133 (17%)
		MH2_I-SMAD	400..565	CDD:199821	57/205 (28%)
daf-3	NP_001300341.1	MH1_SMAD_4	218..346	CDD:199816
		DWB	659..860	CDD:197770	57/206 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910