Protein Alignment Dad and sma-2

DIOPT Version :9

• Sequence 1: NP_001369021.1
• Gene: Dad / 42059
• FlyBaseID: FBgn0020493
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_001370321.1
• Gene: sma-2 / 176229
• WormBaseID: WBGene00004856
• Length: 418
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 94/409 - (22%)
• Similarity: 153/409 - (37%)
• Gaps: 106/409 - (25%)

  Fly   218 REDFEALMKQLKRKQRNEL-LLAVKSRLDPPTKTQRDVVEPTTTTAPTYLQCILIPCKTQTVWE- 280
            ::..:.|||:|.:..:..| .|....|.....||                :|:.||.......:
 Worm    27 KKAIDNLMKKLIKHNKQALENLEFALRCQGQQKT----------------ECVTIPRSLDGRLQI 75

  Fly   281 ------PHVTASRLFFWRELWNAKELKRLPTCPAARDCIY-----MCCNPLHWFRILHQPETESP 334
                  |||...|::.|.:|.:..|||.:..|   |.|..     :|.||.|:.|: |......|
 Worm    76 SHRKALPHVIYCRVYRWPDLQSHHELKAIEDC---RFCYESGQKDICINPYHYKRV-HATGVLPP 136

  Fly   335 T--------PPYQRSKMLRLKDADFEEDSQNDAKSAALSTWSAESTSISNI---------YKPAL 382
            .        ||.:....|    |.|:....:.::       ..::.:::|:         |.|..
 Worm   137 VLVPRYSEKPPQEVPPTL----AKFQLMEMSGSR-------MPQNVNMANVNFTANQFHQYNPNG 190

  Fly   383 YESVTTDGK--------------DHNINSQVWCQIAYWEMAHRVGEFFHAKTNAVNIYTDGIVAS 433
            .|.:.|..|              |.....|.|..::|:|:..||||  ..|.::..|..||..
 Worm   191 IEEMDTSQKFDIPPGVPTCLVPFDKVWEEQFWATVSYYELNTRVGE--QVKVSSTTITIDGFT-- 251

  Fly   434 EVDSMCLRDLTPAGNQI----------HSVVPKARHTVGLGVTLSL--ENGDVWIYNRGNTTIFV 486
               ..|:.     |::|          ::.:...|..:|.||.|:.  .||.::.....::.|||
 Worm   252 ---DPCIN-----GSKISLGLFSNVNRNATIENTRRHIGNGVKLTYVRSNGSLFAQCESDSAIFV 308

  Fly   487 DSPTLSE----NLDRVCKVMPGYCLKAF--ETNRAELLSMRDHGHHPMGPVDYFS-IKISFGKGW 544
            .|...:.    :...|.|:.....||.|  |..|..|......|......:...: |::||.|||
 Worm   309 QSSNCNYINGFHSTTVVKIANKCSLKIFDMEIFRQLLEDCSRRGFDASFDLQKMTFIRMSFVKGW 373

  Fly   545 GRDYKRQDIMGCPCWLEVH 563
            |.:|:|||:...|||:|:|
 Worm   374 GAEYQRQDVTSTPCWIEIH 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dad	NP_001369021.1	MH1_SMAD_6_7	197..329	CDD:199813	30/123 (24%)
		MH2_I-SMAD	400..565	CDD:199821	50/183 (27%)
sma-2	NP_001370321.1	MH1	5..130	CDD:412134	29/122 (24%)
		MH2_R-SMAD	222..405	CDD:199820	50/183 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3701
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810