Protein Alignment Dad and tag-68

DIOPT Version :10

• Sequence 1: NP_001369021.1
• Gene: Dad / 42059
• FlyBaseID: FBgn0020493
• Length: 665
• Species: Drosophila melanogaster
• Sequence 2: NP_492746.2
• Gene: tag-68 / 172930
• WormBaseID: WBGene00006445
• Length: 415
• Species: Caenorhabditis elegans
• Alignment Length: 440
• Identity: 92/440 - (20%)
• Similarity: 149/440 - (33%)
• Gaps: 144/440 - (32%)

  Fly   215 KRFREDFEALMKQLKRKQRNELLLAVKS------------------RLDPPTKTQRDVVEPTTTT 261
            :|.|..|..||:....:....:..||:|                  ..|||.:....:.:.....
 Worm    31 RRARRRFLRLMRGFDAEDVEVIRKAVESDGVDSKACAPGPPMDERVEEDPPDEDSGLIPQIDRPM 95

  Fly   262 APTYLQCILIPCKTQTVWEPHVTASRLFFWRELWNAKELKRLPTCPAAR-------DCIYMCCNP 319
            :..||.|                  :|:.|::|.....|.||...|..|       :....||||
 Worm    96 SMPYLCC------------------KLWRWKDLQVDAALHRLEALPWCRFGRVTINNATVSCCNP 142

  Fly   320 LH---WFRILHQPETESPTPPYQRSKMLRLKDADFEEDS-----QNDAKSAALS----------- 365
            .|   |.|    |||..             .|.|..||.     ||:.:|:.:.
 Worm   143 YHYALWIR----PETNG-------------GDDDGSEDKNSSVPQNNHRSSLIGNGHITYRHRDH 190

  Fly   366 TWSAESTSISNIY----------------------KPALYESVTTDGKD-----HNINSQVWCQI 403
            |..||.:.:..|.                      .|......:.|..|     |:.:::.|.::
 Worm   191 THDAEMSKLPKILAGELPDRPPPSVPNATPPLPDDSPPCTSRSSQDPDDLIHYHHHESNRSWAKM 255

  Fly   404 AYWEMAHRVGE--FFHAKTNAVNIYTDGI-----------VASEVDSMCLRDLTPAGNQIHSVVP 455
            ..:|...::|:  :.|....||.:.:..:           :.:||....:|...|.|    |..|
 Worm   256 TRYERKEQIGDTVWLHGPFAAVGVLSKSVHDAQLECSPWDLKNEVSFALIRQADPIG----STNP 316

  Fly   456 KARHTVGLGVTLSLENGDVWIYNRGNTTIFVD-SPTLSENLDRVCKVMPGYCLKAF--ETNRAEL 517
            :                |||:||.|...:|:. :|.:|...|.:.::.||||::..  |.:.:..
 Worm   317 E----------------DVWLYNSGTRPLFLSMTPNVSSTKDTLRRLSPGYCIRVHRGEVSASAP 365

  Fly   518 LSMRDHGHHPM--GPVDYFSIKISFGKGWGRDYKRQDIMGCPCWLEVHFS 565
            .|.|.....|.  ..:...::.||.|||||.:|.|..:...||..||.|:
 Worm   366 ASERTKVRRPSKDPALAQQNLVISVGKGWGPNYSRLYLTDIPCRYEVSFA 415

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dad	NP_001369021.1	MH1_SMAD_6_7	197..329	CDD:199813	29/141 (21%)
		MH2_I-SMAD	400..565	CDD:199821	44/182 (24%)
tag-68	NP_492746.2	MH1_SMAD_6_7	14..152	CDD:199813	29/142 (20%)
		MH2	251..415	CDD:469593	44/183 (24%)