DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5220 and TRM7

DIOPT Version :9

Sequence 1:	NP_650590.1	Gene:	CG5220 / 42056	FlyBaseID:	FBgn0038471	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_009617.3	Gene:	TRM7 / 852353	SGDID:	S000000265	Length:	310	Species:	Saccharomyces cerevisiae

Alignment Length:	296	Identity:	134/296 - (45%)
Similarity:	188/296 - (63%)	Gaps:	26/296 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILN--GVQRAVDLCAAPGSWSQVLSRKL 63
            |||:||||||:|||:||::|:|||||||||.:::.:..|:  .::|.||||||||||||||||||
Yeast     1 MGKSSKDKRDLYYRKAKEQGYRARSAFKLLQLNDQFHFLDDPNLKRVVDLCAAPGSWSQVLSRKL 65

  Fly    64 YDTCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPD 128
            :|...:.|::.. ||::||||.|:||..:..||.|||...|...|:..| |||||..|..|||||
Yeast    66 FDESPSSDKEDR-KIVSVDLQPMSPIPHVTTLQADITHPKTLARILKLF-GNEKADFVCSDGAPD 128

  Fly   129 VTGVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSS 193
            |||:|::|||:|.||:::||.:..|:|:.|||||||||:|....:|.||:...|.|....||.||
Yeast   129 VTGLHDLDEYVQQQLIMSALQLTACILKKGGTFVAKIFRGRDIDMLYSQLGYLFDKIVCAKPRSS 193

  Fly   194 RPSSIEAFVVCSDFCLPEGYIPQV-INPARDDI--------RLLAQKTG--SEVNRRLVPFIACG 247
            |.:|:|||:||..:..|..:.|:: :|.:.|:.        ..::.|..  :|..|.:..|:|||
Yeast   194 RGTSLEAFIVCLGYNPPSNWTPKLDVNTSVDEFFQGCFLNKLCISDKLSHWNEEERNIAEFMACG 258

  Fly   248 DL---------NGLSDPEEGKTSSSD--ESKSNLEY 272
            .|         :.|.....|.:||.|  :|.:|..|
Yeast   259 SLQSFDSDATYHDLPSSVAGTSSSLDPVQSPTNPPY 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5220	NP_650590.1	RlmE	3..211	CDD:223370	112/209 (54%)
TRM7	NP_009617.3	RlmE	1..211	CDD:223370	114/211 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157344497
Domainoid	1	1.000	190	1.000	Domainoid score	I637
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5372
Inparanoid	1	1.050	233	1.000	Inparanoid score	I717
Isobase	1	0.950	-	0	Normalized mean entropy	S638
OMA	1	1.010	-	-		QHG54241
OrthoFinder	1	1.000	-	-		FOG0004400
OrthoInspector	1	1.000	-	-		otm46558
orthoMCL	1	0.900	-	-		OOG6_102125
Panther	1	1.100	-	-	LDO	PTHR10920
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1803
SonicParanoid	1	1.000	-	-		X3115
TreeFam	0	0.000	Not matched by this tool.
	15	14.780