DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5220 and Ftsj1

DIOPT Version :9

Sequence 1:	NP_650590.1	Gene:	CG5220 / 42056	FlyBaseID:	FBgn0038471	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_598752.2	Gene:	Ftsj1 / 54632	MGIID:	1859648	Length:	324	Species:	Mus musculus

Alignment Length:	280	Identity:	154/280 - (55%)
Similarity:	195/280 - (69%)	Gaps:	24/280 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65
            ||:|||||||:|||.||:.|||||||||||.:||.:.:..||:|||||||||||||||||:|:
Mouse     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDEEFQLFKGVKRAVDLCAAPGSWSQVLSQKV-- 63

  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130
                 ..:.:.:::|||||||||:.|::|:|||||:.|||:.||.||.|. .|.|||||||||||
Mouse    64 -----GGQGSGQVVAVDLQAMAPLPGVIQIQGDITQLSTAKEIIQHFEGC-PADLVVCDGAPDVT 122

  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195
            |:|::|||||.|||:|||:|||.||:.||.||||||:|...:||.||::|||......||.|||.
Mouse   123 GLHDVDEYMQAQLLLAALNIATHVLKLGGCFVAKIFRGRDVTLLYSQLRIFFSSVLCAKPKSSRN 187

  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINPARDDIRLLAQKTGSEVN------RRLVPFIACGDLNGLSD 254
            ||||||.||..:..|||:||.:..|      ||.....::.|      |.:|||:|||||:..
Mouse   188 SSIEAFAVCQGYDPPEGFIPDLTRP------LLNHSYDTDFNQLDGPTRVIVPFVACGDLSAY-- 244

  Fly   255 PEEGKTSSSDESKSNLEYVY 274
             :..:|.|.|....: ||.|
Mouse   245 -DSDRTYSLDLDGGS-EYKY 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5220	NP_650590.1	RlmE	3..211	CDD:223370	128/207 (62%)
Ftsj1	NP_598752.2	RlmE	4..203	CDD:223370	128/206 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840852
Domainoid	1	1.000	217	1.000	Domainoid score	I2663
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5372
Inparanoid	1	1.050	275	1.000	Inparanoid score	I2934
Isobase	1	0.950	-	0	Normalized mean entropy	S638
OMA	1	1.010	-	-		QHG54241
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	1	1.000	-	-		FOG0004400
OrthoInspector	1	1.000	-	-		oto95393
orthoMCL	1	0.900	-	-		OOG6_102125
Panther	1	1.100	-	-	LDO	PTHR10920
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1803
SonicParanoid	1	1.000	-	-		X3115
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	18	17.750