DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5220 and ftsj1

DIOPT Version :9

Sequence 1:	NP_650590.1	Gene:	CG5220 / 42056	FlyBaseID:	FBgn0038471	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_001007385.2	Gene:	ftsj1 / 492512	ZFINID:	ZDB-GENE-041114-83	Length:	323	Species:	Danio rerio

Alignment Length:	277	Identity:	170/277 - (61%)
Similarity:	201/277 - (72%)	Gaps:	15/277 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65
            ||::||||||||||.||:||||||||||||.:||.:.:..||.||||||||||||||||||||
Zfish     1 MGRSSKDKRDIYYRLAKEEGWRARSAFKLLQLDEEFKLFKGVSRAVDLCAAPGSWSQVLSRKL-- 63

  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130
              ...|:...|||:|||||||||:.|:.|:||||||.||||.||.||.| |.|.|||||||||||
Zfish    64 --RGKDKSEEVKIVAVDLQAMAPLPGVTQIQGDITKISTAEEIIRHFEG-ESADLVVCDGAPDVT 125

  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195
            |:|::|||:|.|||:|||:|.|.||:.||.||||||:|...:||.||::|||......||||||.
Zfish   126 GLHDVDEYIQAQLLLAALNITTHVLKPGGNFVAKIFRGKDVTLLYSQLKIFFSFVTCAKPPSSRN 190

  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINPARD---DIRLLAQKTGSEVNRRLVPFIACGDLNGLSDPEE 257
            |||||||||.::..||||:|.:.||..|   |:. |.|..|.  ||.:|||:|||||:|. |.:.
Zfish   191 SSIEAFVVCQNYSPPEGYVPNMSNPLLDHSYDVD-LNQLEGP--NRIIVPFLACGDLSGF-DSDR 251

  Fly   258 GKTSSSDESKSNLEYVY 274
            ......|.||   ||.|
Zfish   252 TYPLQLDSSK---EYQY 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5220	NP_650590.1	RlmE	3..211	CDD:223370	138/207 (67%)
ftsj1	NP_001007385.2	RlmE	5..206	CDD:223370	138/205 (67%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170585326
Domainoid	1	1.000	235	1.000	Domainoid score	I2311
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5372
Inparanoid	1	1.050	305	1.000	Inparanoid score	I2627
OMA	1	1.010	-	-		QHG54241
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	1	1.000	-	-		FOG0004400
OrthoInspector	1	1.000	-	-		oto41595
orthoMCL	1	0.900	-	-		OOG6_102125
Panther	1	1.100	-	-	LDO	PTHR10920
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1803
SonicParanoid	1	1.000	-	-		X3115
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800