DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG5220 and FTSJ1

DIOPT Version :9

Sequence 1:	NP_650590.1	Gene:	CG5220 / 42056	FlyBaseID:	FBgn0038471	Length:	302	Species:	Drosophila melanogaster
Sequence 2:	NP_036412.1	Gene:	FTSJ1 / 24140	HGNCID:	13254	Length:	329	Species:	Homo sapiens

Alignment Length:	293	Identity:	154/293 - (52%)
Similarity:	192/293 - (65%)	Gaps:	43/293 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGKTSKDKRDIYYRQAKDEGWRARSAFKLLHVDEAYGILNGVQRAVDLCAAPGSWSQVLSRKLYD 65
            ||:|||||||:|||.||:.|||||||||||.:|:.:.:..||.|||||||||||||||||:|:
Human     1 MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLSQKI-- 63

  Fly    66 TCETDDEKSAVKIIAVDLQAMAPIRGILQLQGDITKQSTAEAIIGHFGGNEKAQLVVCDGAPDVT 130
                 ..:.:..::|||||||||:.|::|:|||||:.|||:.||.||.|. .|.|||||||||||
Human    64 -----GGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGC-PADLVVCDGAPDVT 122

  Fly   131 GVHEMDEYMQHQLLVAALSIATCVLETGGTFVAKIFKGNATSLLSSQMQIFFKKFDIYKPPSSRP 195
            |:|::|||||.|||:|||:|||.||:.||.||||||:|...:||.||:|:||......||.|||.
Human   123 GLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCAKPRSSRN 187

  Fly   196 SSIEAFVVCSDFCLPEGYIPQVINPARD-----DIRLLAQKTGSEVNRRLVPFIACGDLNGLSDP 255
            ||||||.||..:..|||:||.:..|..|     |...|...|     |.:|||:.||||:.
Human   188 SSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPDFNQLDGPT-----RIIVPFVTCGDLSS---- 243

  Fly   256 EEGKTSSSDESKSNLEYVYDAVMDDASYPLEFK 288
                              ||:   |.||||:.:
Human   244 ------------------YDS---DRSYPLDLE 255

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5220	NP_650590.1	RlmE	3..211	CDD:223370	127/207 (61%)
FTSJ1	NP_036412.1	RlmE	4..203	CDD:223370	127/206 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150790
Domainoid	1	1.000	216	1.000	Domainoid score	I2694
eggNOG	1	0.900	-	-		E1_COG0293
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5372
Inparanoid	1	1.050	272	1.000	Inparanoid score	I3002
Isobase	1	0.950	-	0	Normalized mean entropy	S638
OMA	1	1.010	-	-		QHG54241
OrthoDB	1	1.010	-	-		D1362679at2759
OrthoFinder	1	1.000	-	-		FOG0004400
OrthoInspector	1	1.000	-	-		otm40504
orthoMCL	1	0.900	-	-		OOG6_102125
Panther	1	1.100	-	-	LDO	PTHR10920
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1803
SonicParanoid	1	1.000	-	-		X3115
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	18	17.750