Protein Alignment CG18213 and SMYD1

DIOPT Version :10

• Sequence 1: NP_650589.2
• Gene: CG18213 / 42055
• FlyBaseID: FBgn0038470
• Length: 879
• Species: Drosophila melanogaster
• Sequence 2: NP_938015.1
• Gene: SMYD1 / 150572
• HGNCID: 20986
• Length: 490
• Species: Homo sapiens
• Alignment Length: 523
• Identity: 97/523 - (18%)
• Similarity: 174/523 - (33%)
• Gaps: 131/523 - (25%)

  Fly   238 KSGGVFASCDVPKGEIVLVE---NPVYFQFSAPFLNCELCGVHQQQLYTCDNCRYRSYCSKSCMK 299
            |..|:.|:.:....:|:..|   :.|.|.....|: |..|...|::|:.|..|::..||.::|.|
Human    17 KGRGLKATKEFWAADIIFAERAYSAVVFDSLVNFV-CHTCFKRQEKLHRCGQCKFAHYCDRTCQK 80

  Fly   300 SDAEVHQYECYGYK-IGLIP----MLEANMLFRLFCEAGEYILPAIVDYAMDGGILSNPRDAWTF 359
            .....|:.||...| .|.:|    .|.|.:::|:..|.          ..:..|.|.:..|....
Human    81 DAWLNHKNECSAIKRYGKVPNENIRLAARIMWRVEREG----------TGLTEGCLVSVDDLQNH 135

  Fly   360 ILEHAQEEEKTYNL-VGELLATAPDYNLLTREKYTEIVTTAFRLSVFIYNDTR----LAEKYFYL 419
            :....:||:|...: |...|...|..:.....:|...:......:.|..:|.|    :....|..
Human   136 VEHFGEEEQKDLRVDVDTFLQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPN 200

  Fly   420 LALVKTDLITVMAAILLRLGGHVLLNSQRDNLCYRQREGIDAMNENNDEFENCGILPMPTDRISA 484
            |.||..| ......::...|.|               |.:.:|.......|...:     .:||.
Human   201 LGLVNHD-CWPNCTVIFNNGNH---------------EAVKSMFHTQMRIELRAL-----GKISE 244

  Fly   485 NVFSYYGVNAITDFVDCYNNVHDSLAEIEPEYPEKFSNDSPIFRFADRLHSICMQKYEIEAVEDL 549
                  |......::|..|...:...:::.:|            :.|.....|.:|.:    :||
Human   245 ------GEELTVSYIDFLNVSEERKRQLKKQY------------YFDCTCEHCQKKLK----DDL 287

  Fly   550 ---VSADTLPEQE-INEILQIFNTSQRCQLLTNIAKYFQQFVYQYFHKI--------------EN 596
               |..:..|.|| :.|::|....:     |..|.|...:.:|....|:              .|
Human   288 FLGVKDNPKPSQEVVKEMIQFSKDT-----LEKIDKARSEGLYHEVVKLCRECLEKQEPVFADTN 347

  Fly   597 TVQLKSTLCVT-----LKAFKQ-----NCGTKNIKAIFLPNGKVVGVTAKKV-----HKGEELV- 645
            ...|:....|:     |:||::     .........::.||...:|:...:.     |.|...|
Human   348 IYMLRMLSIVSEVLSYLQAFEEASFYARRMVDGYMKLYHPNNAQLGMAVMRAGLTNWHAGNIEVG 412

  Fly   646 ---IC-----------------PDFARYRDQSRI-LDLARRGDFNF----STSIENEYENLEKMP 685
               ||                 .|....|.|:.: |.:.|:.:|.:    ..::.|:...:...|
Human   413 HGMICKAYAILLVTHGPSHPITKDLEAMRVQTEMELRMFRQNEFMYYKMREAALNNQPMQVMAEP 477

  Fly   686 SPE 688
            |.|
Human   478 SNE 480

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG18213	NP_650589.2	None
SMYD1	NP_938015.1	SET_SMYD1	7..281	CDD:380924	59/313 (19%)
		zf-MYND	52..90	CDD:460312	11/37 (30%)