DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4009 and ALPHA DOX2

DIOPT Version :9

Sequence 1:	NP_001262655.1	Gene:	CG4009 / 42054	FlyBaseID:	FBgn0038469	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_001185393.1	Gene:	ALPHA DOX2 / 843703	AraportID:	AT1G73680	Length:	640	Species:	Arabidopsis thaliana

Alignment Length:	590	Identity:	142/590 - (24%)
Similarity:	215/590 - (36%)	Gaps:	167/590 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    89 DTRNLHYRTLDGSCNNLLYPEFGIAVSRYRRLLPPRQ------------VEQAPNARLISLSLYG 141
            ||....|||.||.||:......|...|...|.:||..            .|......:::..|..
plant    78 DTDEFCYRTADGKCNHPSDNTIGSQGSFIGRNMPPSTSQYGFFCQYFFFPENLEKKIVVATKLLA 142

  Fly   142 EQ---TRNDRFRTMAAMQWGQFVAHD-ISQLSTQGAPQDCCAEPRHPRCL--PINLPRGGPIAYH 200
            .:   ...|:|..:|. .|.||:.|| :..|           |..|...|  |..:..|.|:
plant   143 RKRFIDNGDQFNVIAC-SWIQFMIHDWVDHL-----------EDTHQIELEAPEEVASGCPL--- 192

  Fly   201 TGKTCLHFARSVSDADAICPKVEEPQPEKLTVATAYLDLSSIYGNNPSQNRKVRLFKGGLLKTSY 265
               ....|.|:..     .|..:..:...:...|.:.|.|.||||:.:..|:||:||.|.||.|
plant   193 ---KSFKFLRTKK-----VPTDDHHKSGAVNTRTPWWDGSVIYGNDETGMRRVRVFKDGKLKIS- 248

  Fly   266 TNGQHWLPVSQNENGECGAKSECYIVP---DIRNRFSPTIALLQTLLVREHNRLAENLALINPDH 327
              |...|  .::|.|          ||   ||||.:| ..:|||.|.|:|||.:.:.|....||.
plant   249 --GDGLL--ERDERG----------VPISGDIRNSWS-GFSLLQALFVKEHNSVCDMLKERYPDF 298

  Fly   328 SDERIFQEARKINIAQFQKITYYDWL----------------------------------PLFVG 358
            .||::::.||.:..|...|:...||.                                  |||.|
plant   299 DDEKLYRTARLVTAAVIAKVHTIDWTIELLKTDTLTAGMRINWYGFFGKKVKDMVGARFGPLFSG 363

  Fly   359 RTYTYLNGLIYPVEPTEYVNDYDETVNPAAYAEFSAAAFRYAHTQIPGWFSLVAPNRRSNRTMRL 423
                 |.||..|       ||:..   |.:..|...:.:| .|..:|.  :|:..:..|....:.
plant   364 -----LVGLKKP-------NDHGV---PYSLTEEFVSVYR-MHCLLPE--TLILRDMNSENVDKE 410

  Fly   424 SDFLDR----TETI--------------RLLD----------TSDNFDALLRGLATQLHKRSDGN 460
            :..::|    ||.|              :||.          |..|:...:|.|..|       :
plant   411 NPAIEREIPMTELIGKKAGEKASKLGFEQLLVSMGHQSCGALTLWNYPNWMRNLVAQ-------D 468

  Fly   461 IDREIKHYFNRKEFEEYGSDLKSIDIQRARDFGLASYNDVREFCGLRRAVDWADFAHEIPGEKIS 525
            ||.|.:.:.         .|:.:::|.|.|:.|:..||:.|:...:.....|.:...:  .|.|.
plant   469 IDGEDRPHL---------IDMAALEIYRDRERGVPRYNEFRKNLLMSPISKWEELTDD--EEAIK 522

  Fly   526 LLRRLYATPDDVE---LGVGGTLEYHVPDALFGPTLLCVIGKQFLNTRR--GDRFFFERENEGGF 585
            :||.:|  .||:|   |.||...|..:.......|...:.  ..:.:||  .||||....||..:
plant   523 VLREVY--EDDIEKLDLNVGLHAEKKIKGFAISETAFFIF--LLVASRRLEADRFFTTNFNEKTY 583

  Fly   586 SRAQL 590
            ::..|
plant   584 TKEGL 588

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	85/332 (26%)
		An_peroxidase	95..610	CDD:281139	140/584 (24%)
		peroxinectin_like	228..605	CDD:188655	108/433 (25%)
ALPHA DOX2	NP_001185393.1	PLN02283	1..640	CDD:177921	142/590 (24%)
ALPHA DOX2	NP_001185393.1	An_peroxidase	84..609	CDD:281139	140/584 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2076
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3334
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870