Protein Alignment CG4009 and PTGS1

DIOPT Version :9

• Sequence 1: NP_001262655.1
• Gene: CG4009 / 42054
• FlyBaseID: FBgn0038469
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_000953.2
• Gene: PTGS1 / 5742
• HGNCID: 9604
• Length: 599
• Species: Homo sapiens
• Alignment Length: 493
• Identity: 112/493 - (22%)
• Similarity: 194/493 - (39%)
• Gaps: 127/493 - (25%)

  Fly   183 HPRCLPINLPRGGPIAYHT-GKTCLHFARSVSDADAICPK-------VEEPQPEKL--------- 230
            :.|.|| ::|:..|....| ||      :.:.||..:..:       :.:||...|
Human   147 YTRILP-SVPKDCPTPMGTKGK------KQLPDAQLLARRFLLRRKFIPDPQGTNLMFAFFAQHF 204

  Fly   231 ---------------TVATAY-LDLSSIYGNNPSQNRKVRLFKGGLLKTSYTNGQHW------LP 273
                           |.|..: :||..|||:|..:..::||||.|.||....:|:.:      .|
Human   205 THQFFKTSGKMGPGFTKALGHGVDLGHIYGDNLERQYQLRLFKDGKLKYQVLDGEMYPPSVEEAP 269

  Fly   274 VSQNENGECGAKSECYIVPDIRNRFSPTIALLQTLLVREHNRLAENLALINPDHSDERIFQEARK 338
            |..:.......:|:..:..::.. ..|.:.|..||.:|||||:.:.|...:|...||::||..|.
Human   270 VLMHYPRGIPPQSQMAVGQEVFG-LLPGLMLYATLWLREHNRVCDLLKAEHPTWGDEQLFQTTRL 333

  Fly   339 INIAQFQKITYYDWL--------------PLFVGRTYTYLNGLIYPVEPTEYVNDYDETVNPAAY 389
            |.|.:..||...:::              .|..|..:.|.|.:     ..|:.:.|.  .:|...
Human   334 ILIGETIKIVIEEYVQQLSGYFLQLKFDPELLFGVQFQYRNRI-----AMEFNHLYH--WHPLMP 391

  Fly   390 AEFSAAAFRYAHTQIPGWFSLVAPNRRSNRTMRLSDFLDRTETIRLLDTSDNFDALLRGLATQLH 454
            ..|...:..|::.|                      ||..|.  .|:|.  ..:||:...:.|:.
Human   392 DSFKVGSQEYSYEQ----------------------FLFNTS--MLVDY--GVEALVDAFSRQIA 430

  Fly   455 KRSDG--NIDREIKHYFNRKEFEEYGSDLKSID-IQRARDFGLASYNDVREFCGLRRAVDWADFA 516
            .|..|  |:|..|.|.              ::| |:.:|:..|..:|:.|:..|::   .:..|
Human   431 GRIGGGRNMDHHILHV--------------AVDVIRESREMRLQPFNEYRKRFGMK---PYTSF- 477

  Fly   517 HEIPGEK--ISLLRRLYATPDDVELGVGGTLEYHVPDALFGPTLLCVIGKQF-LNTRRGDRF--- 575
            .|:.|||  .:.|..||...|.:|...|..||...|:::||.::: .||..| |....|:..
Human   478 QELVGEKEMAAELEELYGDIDALEFYPGLLLEKCHPNSIFGESMI-EIGAPFSLKGLLGNPICSP 541

  Fly   576 -FFERENEG---GFSRAQLAEIRK-VSLSSLFCSNANY 608
             :::....|   ||:..:.|.::| |.|::..|...::
Human   542 EYWKPSTFGGEVGFNIVKTATLKKLVCLNTKTCPYVSF 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	56/236 (24%)
		An_peroxidase	95..610	CDD:281139	112/493 (23%)
		peroxinectin_like	228..605	CDD:188655	100/435 (23%)
PTGS1	NP_000953.2	EGF_CA	32..69	CDD:238011
		prostaglandin_endoperoxide_synthase	89..575	CDD:188648	111/487 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7941
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.760