Protein Alignment CG4009 and ptgs2b

DIOPT Version :10

• Sequence 1: NP_650588.2
• Gene: CG4009 / 42054
• FlyBaseID: FBgn0038469
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001020675.1
• Gene: ptgs2b / 559020
• ZFINID: ZDB-GENE-041014-323
• Length: 606
• Species: Danio rerio
• Alignment Length: 623
• Identity: 135/623 - (21%)
• Similarity: 220/623 - (35%)
• Gaps: 185/623 - (29%)

  Fly    58 YNGNNVHN----SWAEPSASQQPLRCGVPPRNCLNDTRNL--HYRTLDGSCNNLLYPEFGIAVSR 116
            |.|.|...    :|.:.|....|           |....:  |:::|....||:.:...||  .|
Zfish    51 YYGQNCTTPEFLTWVKVSLKPSP-----------NTVHYILTHFKSLWNIINNVSFLRNGI--MR 102

  Fly   117 YRRLLPPRQVEQAP--NARLISLSLYGEQTRNDRFRTMAAMQWGQFVAHDISQLSTQGAPQDCCA 179
            |........::..|  ||.      ||.::            |..:     |.||
Zfish   103 YVLTSRAHLIDSPPTFNAD------YGYKS------------WEAY-----SNLS---------- 134

  Fly   180 EPRHPRCLPINLPRGGPIAYH-TGKTCLHFARSVSDADAICPK-------VEEPQPEKLTVA--- 233
              .:.|.|| .:||..|.... .||      :.:.|...:..|       :.:||...|..|
Zfish   135 --YYTRTLP-PVPRDCPTPMGVAGK------KELPDVKMLAEKLLLRRKFIPDPQRTNLMFAFFA 190

  Fly   234 -------------------TAY---LDLSSIYGNNPSQNRKVRLFKGGLLKTSYTNGQHWLPVSQ 276
                               ||.   :||:.|||.|..:..|:||||.|.|:....:|:.:.|
Zfish   191 QHFTHQFFKSDMKKGPAFTTALNHGVDLAHIYGQNLDRQHKLRLFKDGKLRYQILDGEVYPP--- 252

  Fly   277 NENGECGAKSECYI-------VPDIRNRFS---------PTIALLQTLLVREHNRLAENLALINP 325
                   ..||..:       ||:.| ||:         |.:.:..|:.:|||||:.:.|...:|
Zfish   253 -------TVSEVQVDMHYPPHVPESR-RFAVGHEAFGLVPGLMMYATIWLREHNRVCDILKQEHP 309

  Fly   326 DHSDERIFQEARKINIAQFQKITYYDWLPLFVGRTYTYLNGLIYPV--EPTEYVND---YDETVN 385
            |..|||:||.:|.|.|.:..||...|::        .:|:|..:.:  :|....|:   |...::
Zfish   310 DWDDERLFQTSRLILIGETIKIVIEDYV--------QHLSGYYFKLKFDPELLFNERFQYQNRIS 366

  Fly   386 PAAYAEFSAAAFRYAHTQIPGWFSLVAPNRRSNRTMRLSDFLDRTETIRLLDTSDNFDALLRGLA 450
                :||:  ...:.|..:|..|.:      .:.......||..|..:    |....::|:....
Zfish   367 ----SEFN--TLYHWHPLMPDDFHI------QDEVYNYQQFLFNTSIL----TDYGVNSLVESFN 415

  Fly   451 TQLHKRSDGN-------IDREIKHYFNRKEFEEYGSDLKSIDIQRARDFGLASYNDVREFCGLRR 508
            .|:..|..|.       :...||...|.::..     .:||:..|.| |.:..|....|..|.:
Zfish   416 KQIAGRVAGGRNVAPAVLRVAIKSIENSRQMR-----YQSINAYRKR-FNMKPYRSFEEMTGEK- 473

  Fly   509 AVDWADFAHEIPGEKISLLRRLYATPDDVELGVGGTLEYHVPDALFGPTLLCVIGKQFLNTRRGD 573
                         |..:.|..:|...|.|||..|..:|....:|:||.|::.:.....|....|:
Zfish   474 -------------EMAAELEEMYGDVDAVELYAGLLVEKPRSNAIFGETMVEMGAPYSLKGLMGN 525

  Fly   574 RF----FFERENEGGFSRAQLAEIRKVSLSSLFCSNAN 607
            ..    :::....||  :.....:...||.:|.|:|.|
Zfish   526 PICSPEYWKPSTFGG--KVGFEIVNSASLQNLVCNNVN 561

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_650588.2	An_peroxidase	95..617	CDD:460804	127/580 (22%)
ptgs2b	NP_001020675.1	EGF_CA	21..57	CDD:238011	3/5 (60%)
		prostaglandin_endoperoxide_synthase	77..565	CDD:188648	128/586 (22%)