DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4009 and CG42331

DIOPT Version :9

Sequence 1:	NP_001262655.1	Gene:	CG4009 / 42054	FlyBaseID:	FBgn0038469	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_001189281.1	Gene:	CG42331 / 42948	FlyBaseID:	FBgn0259233	Length:	1615	Species:	Drosophila melanogaster

Alignment Length:	681	Identity:	208/681 - (30%)
Similarity:	315/681 - (46%)	Gaps:	86/681 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 YSAMEPSLSRSKRSSFDIRPGVSDGSLDALIKEF-----------MPKY---------NGNNVH- 64
            |..::|.:.|:.::..|..|.       |::..|           |..|         ..|..|
  Fly    88 YGRIQPEMLRNGQTLQDNHPA-------AMLSRFNAPTTDSERREMAAYATIAAAKAFRKNFQHI 145

  Fly    65 NSWAEPSASQQ-PLR-------CGVPPRN---CLNDTRNLHYRTLDGSCNNLLYPEFGIAVSRYR 118
            :..|..|.:|: .||       |  |||:   |:..:.  .|||.||:|||...|.:|.|...:.
  Fly   146 DELARQSHTQRISLRRTALEGLC--PPRDPPPCMPASE--RYRTHDGTCNNKRRPRWGAAQMPFN 206

  Fly   119 RLLPPRQVE------------QAPNARLISLSLYGEQTRNDRFRTMAAMQWGQFVAHDISQL--- 168
            |.|||...:            ...::|.:||.::|.: ..:...|:...||||.:.||::..
  Fly   207 RFLPPEYGDGVDTVRSSADGSTLSSSRFVSLLVHGAR-EGEAPLTLMIAQWGQMLDHDMTSTAQP 270

  Fly   169 -STQGAPQDCC-AEPRHPRCLPINLPRGGPIAYHTGKTCLHFARSVSDADAICPKVEEPQPEKLT 231
             |..|:...|| .:..||.|.||.:|...|........||.|.||.......|......|..::
  Fly   271 RSINGSIPSCCGGKDFHPACFPIKVPLDDPWLAPLKVRCLEFLRSAPAQRRDCVLSWREQTNQV- 334

  Fly   232 VATAYLDLSSIYGNNPSQNRKVRLFKGGLLKTSYTNGQHWLPVSQNENGECGA-KSECYIVPDIR 295
              |:|:|.|.||.|:...:...|:|:.|||  .|..|.....|.|.     || .::|....|.|
  Fly   335 --TSYIDASPIYSNSAKSSDNARVFRHGLL--VYGRGDPAEDVCQR-----GAIATKCIRSGDGR 390

  Fly   296 NRFSPTIALLQTLLVREHNRLAENLALINPDHSDERIFQEARKINIAQFQKITYYDWLPLFVGRT 360
            :...|.:..:..:.|.||||:|..|:.:||..|||:::||.|:|..|.||.||:.::||:.:||.
  Fly   391 SGEQPGLLAMHHVWVGEHNRIAMELSELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILGRE 455

  Fly   361 YTYLNGLIYPVEPTEYVNDYDETVNPAAYAEFSAAAFRYAHTQIPGWFSLVAPNRR-SNRTMRLS 424
            ...|..|  .:.|:.|...|...|||.....|:|||||:.|:.:...::....:.. .|..:.|.
  Fly   456 VVKLFDL--ELMPSGYYERYSSKVNPTVANAFAAAAFRFGHSLVQNSYTRCDRHHNVINNNVSLH 518

  Fly   425 DFLDRTETIRLLDTSDNFDALLRGLATQLHKRSDGNIDREI-KHYFNRKEFEEYGSDLKSIDIQR 488
            :...|.:    :.::.:...||||||:|...:.|..|..|: .|.|....| .:|.||.:|:|||
  Fly   519 EEFQRGD----IGSAGSLHRLLRGLASQRALKRDEFITPELTNHLFQTPGF-PFGLDLAAINIQR 578

  Fly   489 ARDFGLASYNDVREFCGLRRAVDWADFAHEIPGEKISLLRRLYATPDDVELGVGGTLEYHVPDAL 553
            .||.|:|.|:..|..|||...:.|.|||:.:..|....:...|.:..|::|.|||..|..|...|
  Fly   579 GRDHGIAPYSAWRVPCGLSPILSWDDFANVVGPESAKRIGHAYRSVHDIDLFVGGIAERPVVGGL 643

  Fly   554 FGPTLLCVIGKQFLNTRRGDRFFFEREN-EGGFSRAQLAEIRKVSLSSLFCSNANYLHLIQPNVF 617
            .|||..|:|.:||.|:||||||::|... |..|:.|||..:|:|||:.:.|..... ..:||::|
  Fly   644 VGPTFACIIAQQFSNSRRGDRFWYENGGFESSFTPAQLHSLRRVSLAQVLCRTVGG-GTLQPHIF 707

  Fly   618 V---FPNSHNLLLNCNFIPQIDLSKWQDLRP 645
            :   |.::.........:..||||.|.:..|
  Fly   708 IPAEFEDNERQTCGVGSLSPIDLSPWLEQDP 738

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	99/317 (31%)
		An_peroxidase	95..610	CDD:281139	177/535 (33%)
		peroxinectin_like	228..605	CDD:188655	133/380 (35%)
CG42331	NP_001189281.1	An_peroxidase	183..699	CDD:281139	177/533 (33%)
CG42331	NP_001189281.1	peroxinectin_like	328..696	CDD:188655	134/384 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920