DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4009 and Ptgs2

DIOPT Version :9

Sequence 1:	NP_001262655.1	Gene:	CG4009 / 42054	FlyBaseID:	FBgn0038469	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_058928.3	Gene:	Ptgs2 / 29527	RGDID:	620349	Length:	604	Species:	Rattus norvegicus

Alignment Length:	399	Identity:	91/399 - (22%)
Similarity:	160/399 - (40%)	Gaps:	85/399 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   237 LDLSSIYGNNPSQNRKVRLFKGGLLKTSYTNGQHWLPVSQNENGECGAKSECYIVPDIRN--RFS 299
            :||:.:||....:..|:|||:.|.||.....|:.:.|..::      .:.:....|.:..  ||:
  Rat   214 VDLNHVYGETLDRQHKLRLFQDGKLKYQVIGGEVYPPTVKD------TQVDMIYPPHVPEHLRFA 272

  Fly   300 ---------PTIALLQTLLVREHNRLAENLALINPDHSDERIFQEARKINIAQFQKITYYDWLPL 355
                     |.:.:..|:.:|||||:.:.|...:|:..|||:||.:|.|.|.:..||...|::
  Rat   273 VGQEVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYV-- 335

  Fly   356 FVGRTYTYLNGLIYPV--EPTEYVNDYDETVNPAAYAEFSAAAFRYAHTQIPGWFSLVAPNRRSN 418
                  .:|:|..:.:  :|....|...:..|..| :||:  ...:.|..:|..|::      .:
  Rat   336 ------QHLSGYHFKLKFDPELLFNQQFQYQNRIA-SEFN--TLYHWHPLLPDTFNI------ED 385

  Fly   419 RTMRLSDFLDRTETI---RLLDTSDNFDALLRG---------LATQLHKRSDGNIDREIKHYFNR 471
            :......||.....:   .|....::|...:.|         :|.|...::..:..||:|:
  Rat   386 QEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGGRNVPIAVQAVAKASIDQSREMKY---- 446

  Fly   472 KEFEEYGSDLKSIDIQRARDFGLASYNDVREFCGLRRAVDWADFAHEIPGEKISLLRRLYATPDD 536
                      :|::..|.| |.|..|....|..|.:              |..:.|:.||...|.
  Rat   447 ----------QSLNEYRKR-FSLKPYTSFEELTGEK--------------EMAAELKALYHDIDA 486

  Fly   537 VELGVGGTLEYHVPDALFGPTLLCVIGKQF-LNTRRGDRF----FFERENEGGFSRAQLAEIRKV 596
            :||.....:|...|||:||.|:: .:|..| |....|:..    :::....||  ......|...
  Rat   487 MELYPALLVEKPRPDAIFGETMV-ELGAPFSLKGLMGNPICSPQYWKPSTFGG--EVGFRIINTA 548

  Fly   597 SLSSLFCSN 605
            |:.||.|:|
  Rat   549 SIQSLICNN 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	37/140 (26%)
		An_peroxidase	95..610	CDD:281139	91/399 (23%)
		peroxinectin_like	228..605	CDD:188655	90/397 (23%)
Ptgs2	NP_058928.3	EGF	21..53	CDD:278437
Ptgs2	NP_058928.3	prostaglandin_endoperoxide_synthase	75..562	CDD:188648	91/399 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810