Protein Alignment CG4009 and Duox2

DIOPT Version :9

• Sequence 1: NP_001262655.1
• Gene: CG4009 / 42054
• FlyBaseID: FBgn0038469
• Length: 649
• Species: Drosophila melanogaster
• Sequence 2: NP_001349684.1
• Gene: Duox2 / 214593
• MGIID: 3036280
• Length: 1545
• Species: Mus musculus
• Alignment Length: 583
• Identity: 170/583 - (29%)
• Similarity: 254/583 - (43%)
• Gaps: 87/583 - (14%)

  Fly    99 DGSCNNLLYPEFGIAVSRYRRLLPPRQ---VEQA------PNARLISLSL-YGE----QTRNDRF 149
            ||..|||.|.:.|.|.||.|||:|...   |.||      ||.|.:|.:: .|:    ...|
Mouse    39 DGWFNNLKYHQRGAAGSRLRRLIPANYADGVYQALEEPLLPNPRRLSDAVAKGKAGLPSVHN--- 100

  Fly   150 RTMAAMQWGQFVAHDISQLSTQGAPQDCCAEPRHPRCLPINLPRGGPI--AYHTGKTCLHFARSV 212
            ||:..:.:|..|..|:..:.|.|.|.:         .|.|.:|||.|:  ....|...|.|.||.
Mouse   101 RTVLGVFFGYHVLSDLVSVETPGCPAE---------FLNIYIPRGDPVFDPDKRGNVVLPFQRSR 156

  Fly   213 SDADAICPKVEEPQPEKLTVATAYLDLSSIYGNNPSQNRKVRLFKGGLL---------KTSYTNG 268
            .|.:. ......|:.:...| |.:||.|:|||::.|.:..:|.|.||.|         :.|.::.
Mouse   157 WDHNT-GQSPSNPRDQSNQV-TGWLDGSAIYGSSHSWSDTLRSFSGGQLASGPDPAFPRNSQSSL 219

  Fly   269 QHWL--PVSQNENGECGAKSECYIVPDIRNRFSPTIALLQTLLVREHNRLAENLALINPDHSDER 331
            ..|:  ..|....|..|.    |.....|....|.:..|..|..|.||..|..||..:|...||.
Mouse   220 LMWMAPDPSTGRGGPQGV----YAFGAQRGNREPFLQALGLLWFRYHNLCARKLAQEHPHWGDEE 280

  Fly   332 IFQEARKINIAQFQKITYYDWLPLFVGRTYTYLNGLIYPVEPTEYVNDYDETVNPAAYAEFSAAA 396
            :||.|||..||.:|.|..|.|||.|:.:|            |.|| :.|...::|:...||..|:
Mouse   281 LFQHARKRVIATYQNIALYQWLPSFLQKT------------PPEY-SGYRPFMDPSISPEFVVAS 332

  Fly   397 FRYAHTQIPGWFSLVAPNRRSNRTMRL--SDFLDRTETIRL-----------LDTSDNFDALLRG 448
            .::..|.:|....:    |.|:...|.  .:..|.:..:|:           |.|:.:.|.||.|
Mouse   333 EQFLSTMVPPGVYM----RNSSCHFRKFPKEGSDSSPALRVCNSYWIRENPNLKTAQDVDQLLLG 393

  Fly   449 LATQLHKRSDGNIDREIKHYFNRKE-FEEYGSDLKSIDIQRARDFGLASYNDVREFCGLRRAVDW 512
            :|:|:.:..|..:..:::.|:...| |..  :|..:..|||.||.||.||:......||....:|
Mouse   394 MASQISELEDRIVIEDLRDYWPGPERFSR--TDYVASSIQRGRDMGLPSYSQALLALGLEPPKNW 456

  Fly   513 ADFAHEIPGEKISLLRRLYATP-DDVELGVGGTLEYHVPDALFGPTLLCVIGKQFLNTRRGDRFF 576
            :....::..:.:.....||... ..:||.:||.||.|...   ||....:|..||:..|.|||::
Mouse   457 SALNPQVEPQVLEATAALYNQDLSQLELLLGGLLESHGDP---GPLFSNIILDQFVRLRDGDRYW 518

  Fly   577 FERENEGGFSRAQLAEIRKVSLSSLFCSNANY-LHLIQPNVFVF----PNSHNLLLNCNFIPQ 634
            ||....|.||:.::||||..:|..:..:.:|. ...:|||||.:    |......|..:.:||
Mouse   519 FENTRNGLFSKEEIAEIRNTTLRDVLVAVSNVDPSALQPNVFFWQEGAPCPQPRQLTTDGLPQ 581

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	92/294 (31%)
		An_peroxidase	95..610	CDD:281139	161/553 (29%)
		peroxinectin_like	228..605	CDD:188655	116/402 (29%)
Duox2	NP_001349684.1	dual_peroxidase_like	38..594	CDD:188652	170/583 (29%)
		EFh	824..885	CDD:238008
		EFh	861..919	CDD:238008
		Ferric_reduct	1085..1229	CDD:366815
		NOX_Duox_like_FAD_NADP	1271..1545	CDD:99783

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910