DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4009 and pxn-2

DIOPT Version :9

Sequence 1:NP_001262655.1 Gene:CG4009 / 42054 FlyBaseID:FBgn0038469 Length:649 Species:Drosophila melanogaster
Sequence 2:NP_509834.1 Gene:pxn-2 / 181288 WormBaseID:WBGene00004257 Length:1328 Species:Caenorhabditis elegans


Alignment Length:620 Identity:203/620 - (32%)
Similarity:296/620 - (47%) Gaps:115/620 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly    95 YRTLDGSCNNLLYPEFGIAVSRYRRLLPPRQVE-----------------QAPNARLISLSLYG- 141
            ||:.||.|||..:|.:|::...:.||||||...                 :.||||.:|..|.| 
 Worm   669 YRSYDGQCNNHEHPWWGVSEMAFMRLLPPRYENGFNTPVGWEKGKRYNGYEVPNARKVSRVLIGT 733

  Fly   142 -EQTRNDRFRTMAAMQWGQFVAHDISQLS--------TQGAPQDCCAEPRHPRCLPINLPRGGPI 197
             |.|.:.....| .||||||:.||::..:        .:||..:...|...| |..|.|....| 
 Worm   734 DETTPHSHLSAM-TMQWGQFIDHDLTLTAPALTRHSYKEGAFCNRTCENADP-CFNIQLEADDP- 795

  Fly   198 AYHTG----KTCLHFARSVSDADAICPKVEEPQP--------EKLTVATAYLDLSSIYGNNPSQN 250
            ..|||    ..|:.|.|:    .|.|.. .|..|        ::|.:.|:|||.|.||||:..|.
 Worm   796 KLHTGLYQKHPCMEFERN----GAACGS-GETSPIFQRVTYRDQLNLLTSYLDASGIYGNSEEQA 855

  Fly   251 RKVR-LFKG-GLLKTSYTNGQH--WLPVSQNENGECGAK------SECYIVPDIRNRFSPTIALL 305
            .::| |:.. |||:....:|.:  ::|..::.:.:|...      .:|::..|:|......:..:
 Worm   856 LELRDLYSDHGLLRFDIVSGANKPYMPFEKDSDMDCRRNFSRENPIKCFLAGDVRANEQLGLMSM 920

  Fly   306 QTLLVREHNRLAENLALINPDHSDERIFQEARKINIAQFQKITYYDWLPLFVGR-TYTYLNGLIY 369
            .|:.:|||||:|..|..:|.:...|.||||.||:..|..|.|||..|||..:|: ||..:.|   
 Worm   921 HTIFLREHNRIASRLLEVNENWDGETIFQETRKLIGAMLQHITYNAWLPKILGKATYNTIIG--- 982

  Fly   370 PVEPTEYVNDYDETVNPAAYAEFSAAAFRYAHT-------------------QIPGWFSLVAPNR 415
                 || ..|:..|||....||:.||.|:|||                   .:|...:..||.|
 Worm   983 -----EY-KGYNPDVNPTIANEFATAALRFAHTLINTHLFRFDKDFKETKQGHLPLHNAFFAPER 1041

  Fly   416 RSNRTMRLSDFLDRTETIRLLDTSDNFDALLRGLATQLHK--RSDGNIDREI-KHYFNRKEFEEY 477
                                |.:....|.|||||.....|  |.|..:::|: :..|||  |.|.
 Worm  1042 --------------------LVSEGGVDPLLRGLFAAPIKMPRPDQVLNKELTEKLFNR--FHEV 1084

  Fly   478 GSDLKSIDIQRARDFGLASYNDVREFCGLRRAVDWADFAHEIPGEK-ISLLRRLYATPDDVELGV 541
            ..||.:::|||.||.||.|:.:.|:||.|.....|:|..:.:..:. ||.|:.||...::::|.|
 Worm  1085 ALDLAALNIQRGRDHGLPSWTEYRKFCNLTVPKTWSDMKNIVQNDTVISKLQSLYGVTENIDLWV 1149

  Fly   542 GGTLEYHVPDALFGPTLLCVIGKQFLNTRRGDRFFFERENEGGFSRAQLAEIRKVSLSSLFCSNA 606
            ||..|....|||.||||.|:|..||...|.||||::  |||..||:|||.:|:||:||.:.|:|.
 Worm  1150 GGVTEKRTADALMGPTLACIIADQFKRLRDGDRFWY--ENEEMFSKAQLRQIKKVTLSKIICTNG 1212

  Fly   607 NYLHLIQPNVFVF-PNSHNLLLNCNFIPQIDLSKW 640
            :.:..||.::||: .||......|..:|:|:|:.|
 Worm  1213 DDIDRIQRDIFVYHGNSTQFYEPCESLPEINLNMW 1247

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4009NP_001262655.1 An_peroxidase_like 77..>367 CDD:265428 100/321 (31%)
An_peroxidase 95..610 CDD:281139 192/587 (33%)
peroxinectin_like 228..605 CDD:188655 140/410 (34%)
pxn-2NP_509834.1 LRRNT 16..43 CDD:396168
leucine-rich repeat 28..44 CDD:275380
PRK15370 <35..>155 CDD:185268
leucine-rich repeat 46..69 CDD:275378
LRR_8 47..104 CDD:404697
leucine-rich repeat 70..93 CDD:275378
leucine-rich repeat 94..116 CDD:275378
leucine-rich repeat 117..140 CDD:275378
leucine-rich repeat 141..154 CDD:275378
Ig 346..432 CDD:416386
Ig strand B 369..373 CDD:409353
Ig strand C 382..386 CDD:409353
Ig strand E 405..410 CDD:409353
Ig strand F 419..424 CDD:409353
I-set 445..533 CDD:400151
Ig strand A' 453..457 CDD:409353
Ig strand B 460..469 CDD:409353
Ig strand C 475..480 CDD:409353
Ig strand C' 483..486 CDD:409353
Ig strand D 491..496 CDD:409353
Ig strand E 497..505 CDD:409353
Ig strand F 512..520 CDD:409353
Ig strand G 523..533 CDD:409353
peroxidasin_like 798..1238 CDD:188658 158/477 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG2408
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D276568at2759
OrthoFinder 1 1.000 - - FOG0000202
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.820

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