DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4009 and bli-3

DIOPT Version :9

Sequence 1:	NP_001262655.1	Gene:	CG4009 / 42054	FlyBaseID:	FBgn0038469	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	NP_490686.3	Gene:	bli-3 / 171608	WormBaseID:	WBGene00000253	Length:	1497	Species:	Caenorhabditis elegans

Alignment Length:	610	Identity:	165/610 - (27%)
Similarity:	254/610 - (41%)	Gaps:	106/610 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 RNLHYRTLDGSCNNLLYPEFGIAVSRYRRLLPPRQV---------EQAPNARLISLSLY-GEQ-T 144
            :|..::..||..|||...|:|.|.||..|  ..|..         ...|:||.:|..|: ||. .
Worm    24 QNEEFQRYDGWYNNLANSEWGSAGSRLHR--DARSYYSDGVYSVNNSLPSARELSDILFKGESGI 86

  Fly   145 RNDRFRTMAAMQWGQFVAHDISQLSTQGAPQDCCAEPRHPRCLPINLPRGGPI--AYHTGKTCLH 207
            .|.|..|.....:.|.||::|.|.:....|.:         .|.|.:|....:  ....|||.:.
Worm    87 PNTRGCTTLLAFFSQVVAYEIMQSNGVSCPLE---------TLKIQVPLCDNVFDKECEGKTEIP 142

  Fly   208 FARSVSDADAICPKVEEPQPEKLTVATAYLDLSSIYGNNPSQNRKVRLFKGGLLKTSY-----TN 267
            |.|:..| .|....:..|: |::...|:::|.|.|||........:|.||.|.|....     .|
Worm   143 FTRAKYD-KATGNGLNSPR-EQINERTSWIDGSFIYGTTQPWVSSLRSFKQGRLAEGVPGYPPLN 205

  Fly   268 GQHWLPVSQNENGECG---AKSECYIVPDIRNRFSPTIALLQTLLVREHNRLAENLALINPDHSD 329
            ..| :|::.....:..   :....:::.|.|...:|.:.....:|.|.||..|..:...:||.:|
Worm   206 NPH-IPLNNPAPPQVHRLMSPDRLFMLGDSRVNENPGLLSFGLILFRWHNYNANQIHREHPDWTD 269

  Fly   330 ERIFQEARKINIAQFQKITYYDWLPLFVGRTYTYLNGLIYPVEPTEYVNDYDETVNPAAYAEFSA 394
            |:|||.||::.||..|||..||::|..:|.          .|..:.|.. |...|.|.....|.|
Worm   270 EQIFQAARRLVIASMQKIIAYDFVPGLLGE----------DVRLSNYTK-YMPHVPPGISHAFGA 323

  Fly   395 AAFRYAHTQIPGWFSLVAPNRRSNRTMRLSDFLDRTE-----TIRLLDTSDN---------FDAL 445
            ||||:.|:.:|....|   .:|.|:    .:|  |||     .:||.....|         .|.:
Worm   324 AAFRFPHSIVPPAMLL---RKRGNK----CEF--RTEVGGYPALRLCQNWWNAQDIVKEYSVDEI 379

  Fly   446 LRGLATQLHKRSDGNIDREIKHY-FNRKEFEEYGSDLKSIDIQRARDFGLASYNDVREFCGLRRA 509
            :.|:|:|:.:|.|..:..:::.| |....|...  |:.:..|.|.||.|:..||::|...||...
Worm   380 ILGMASQIAERDDNIVVEDLRDYIFGPMHFSRL--DVVASSIMRGRDNGVPPYNELRRTFGLAPK 442

  Fly   510 VDW----ADF--AHEIPGEKISLL---RRLYATPDDVELGVGGTLE--YHVPDALFGPTLLCVIG 563
            . |    .||  .|....||:..|   ..||     ::..|||.||  .:.|..||..    :|.
Worm   443 T-WETMNEDFYKKHTAKVEKLKELYGGNILY-----LDAYVGGMLEGGENGPGELFKE----IIK 497

  Fly   564 KQFLNTRRGDRFFFERENEGGFSRAQLAEIRKVSLSSLFCSNANYLH-LIQPNVFVF----PNSH 623
            .||...|.||||:||.:..|.|:..::..|..::|..:..:..:... ::|.:||.|    |...
Worm   498 DQFTRIRDGDRFWFENKLNGLFTDEEVQMIHSITLRDIIKATTDIDETMLQKDVFFFKEGDPCPQ 562

  Fly   624 NLLLN------CNFIPQIDLSKWQD 642
            ...:|      |  :|.:..:.|.|
Worm   563 PFQVNTTGLEPC--VPFMQSTYWTD 585

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	81/296 (27%)
		An_peroxidase	95..610	CDD:281139	154/561 (27%)
		peroxinectin_like	228..605	CDD:188655	115/410 (28%)
bli-3	NP_490686.3	An_peroxidase	28..542	CDD:281139	154/559 (28%)
		dual_peroxidase_like	31..586	CDD:188652	164/603 (27%)
		FRQ1	784..932	CDD:227455
		Ferric_reduct	1035..1176	CDD:280043
		NOX_Duox_like_FAD_NADP	1218..1402	CDD:99783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910