DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4009 and epx

DIOPT Version :9

Sequence 1:	NP_001262655.1	Gene:	CG4009 / 42054	FlyBaseID:	FBgn0038469	Length:	649	Species:	Drosophila melanogaster
Sequence 2:	XP_021326443.1	Gene:	epx / 100331172	ZFINID:	ZDB-GENE-130425-2	Length:	828	Species:	Danio rerio

Alignment Length:	718	Identity:	196/718 - (27%)
Similarity:	301/718 - (41%)	Gaps:	148/718 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VSDGS-----LDALIKEFMPK---------YNGNNVH--------NSWAEPSASQ---------- 74
            :|:||     |.||.|:..||         :..|.|.        :|..:|..|:
Zfish     3 LSEGSVRPNDLLALFKQTGPKTKAHIRAAEFLDNTVELIREMVYTHSMDKPDLSELLSAEDMETI 67

  Fly    75 -QPLRCGVPPRN--CLNDTRNLHYRTLDGSCNNLLY----PEFGIAVSRYRR------------- 119
             |...|....:.  |.:|..:..|||:.|.|||..:    |::|.|.:.|.|
Zfish    68 LQATGCSAEMKRPVCKSDCLSKRYRTITGHCNNSYFDRENPQWGAANTPYARWLSPQYEDPRGAP 132

  Fly   120 ------------LLPPRQVEQAPNARLISLSLYGEQTRN---DRFRTMAAMQWGQFVAHDISQLS 169
                        .|||.::...||.|.:|..:...|..|   |...:...::|||::.||::  .
Zfish   133 RGWSPQHTYHNHTLPPVRLTAVPNVRRVSQEVLYTQNGNITLDGSLSHLLVEWGQWIDHDLT--L 195

  Fly   170 TQGAPQ--------DC---CAEPRHPRCLPINLPRGGPIAYHTGKTCLHFARSVSDADAICPKVE 223
            |..:|.        ||   |:  ....|.||.:|...|.: || ::|:.|.||       .|...
Zfish   196 TPQSPSTAAFRTRADCTRTCS--TDTPCFPIQIPLSDPRS-HT-QSCMAFFRS-------APSCS 249

  Fly   224 EP--QPEKLTVATAYLDLSSIYGNNPSQNRKVRLFKG--GLLKTSY------------------- 265
            .|  |.|:|...||::|.|.:||::.:....:|....  |||..:.
Zfish   250 SPLGQREQLNAITAFVDSSMVYGSSDALALSLRNLSSPLGLLAVNQFHSDQGFDFMPFLNRTQPQ 314

  Fly   266 -------TNGQHWLPVSQNENGECGAKSECYIVPDIRNRFSPTIALLQTLLVREHNRLAENLALI 323
                   .:..|.....||.|...|..|.|:...|.|......:..|.||.:|||||||:.|..|
Zfish   315 LDPCGPRQHSDHTTAPQQNNNISMGNASFCFQAGDSRANEHLGMIALHTLFLREHNRLAKELHRI 379

  Fly   324 NPDHSDERIFQEARKINIAQFQKITYYDWLPLFVGRTYTYLNGLIYPVEPTEYVNDYDETVNPAA 388
            ||..|.:.::||||||..|..|.:|:..:||..:||:   .|.::.|.     ...||...:|:.
Zfish   380 NPHWSPDTLYQEARKILGAVHQILTWDHYLPHVLGRS---ANQILMPA-----YKGYDPAADPSI 436

  Fly   389 YAEFSAAAFRYAHTQIPGWFSLVAPNRR---SNRTMRLSDFLDRTETIRLLDTSDNFDALLRGLA 450
            ...||.||||:||..:....:.:.|:.|   ::..:.|...|..:..:   ......|.:||||.
Zfish   437 SNIFSTAAFRFAHVTVHPVVNRLGPDYRLSPAHPALPLHHSLFASWRV---VKEGGIDPVLRGLL 498

  Fly   451 TQLHKRSDGNIDREIKHYFNRKEFEEYGS---DLKSIDIQRARDFGLASYNDVREFCGLRRAVDW 512
            ....|..  ..|:.:......:.|:..|.   ||.::::||.||.||..|:..||.|||...|:.
Zfish   499 VSPAKLQ--TADQMMVEELTERLFQAQGGLPLDLAALNLQRGRDHGLQGYSVWRELCGLPAPVNE 561

  Fly   513 ADFAHEIPGEKIS-LLRRLYATPDDVELGVGGTLEYHVPDALFGPTLLCVIGKQFLNTRRGDRFF 576
            :..:..:....:: .|..||...:::::.||...|..:|....||.|.|:|.:||...|.||||:
Zfish   562 SALSGILGNTALARKLLDLYGVAENIDVWVGAIAEPALPGGRVGPLLACLIARQFRGLRDGDRFW 626

  Fly   577 FERENEGGFSRAQLAEIRKVSLSSLFCSNANYLHLIQPNVFVFPNS--HNLLLNCNFIPQIDLSK 639
            :  :|||.||..|...:|..|||.:.|.|.   |:.|..:..|.|:  ...||:|:.|...:||.
Zfish   627 W--QNEGVFSSGQRDALRSTSLSRIICENT---HIQQVPLDPFTNTMRPEELLSCSNIQLFNLSA 686

  Fly   640 WQD 642
            |.:
Zfish   687 WTE 689

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4009	NP_001262655.1	An_peroxidase_like	77..>367	CDD:265428	99/364 (27%)
		An_peroxidase	95..610	CDD:281139	167/594 (28%)
		peroxinectin_like	228..605	CDD:188655	120/411 (29%)
epx	XP_021326443.1	An_peroxidase_like	111..689	CDD:326323	170/608 (28%)
		CCP	<711..747	CDD:153056
		EGF_CA	748..>775	CDD:214542
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584260
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	1	1.000	-	-		FOG0000202
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.850