Protein Alignment CG5225 and MARCO

DIOPT Version :10

• Sequence 1: NP_650587.1
• Gene: CG5225 / 42053
• FlyBaseID: FBgn0038468
• Length: 594
• Species: Drosophila melanogaster
• Sequence 2: NP_006761.1
• Gene: MARCO / 8685
• HGNCID: 6895
• Length: 520
• Species: Homo sapiens
• Alignment Length: 333
• Identity: 99/333 - (29%)
• Similarity: 110/333 - (33%)
• Gaps: 128/333 - (38%)

  Fly    56 PPPPPPPPPPPQH----------CNCPPGPPGPP---------GPPGLP------GTPGPQGPKG 95
            |..|.||.||.:.          ...|.||.|||         ||.|.|      |||||||.||
Human   165 PGAPGPPGPPAEKGAKGAMGRDGATGPSGPQGPPGVKGEAGLQGPQGAPGKQGATGTPGPQGEKG 229

  Fly    96 HTGS------KGERGEKGERGHYGLPGQPGEPGPIGPPGLPGPPGHKSGHGHHDHHDHHHHHPAP 154
            ..|.      |||.|.|||:|..||||..|:.|..|..|:.||||.:...|....
Human   230 SKGDGGLIGPKGETGTKGEKGDLGLPGSKGDRGMKGDAGVMGPPGAQGSKGDFGR---------- 284

  Fly   155 PPPPPPPPPPPPPPPPPHSHPHSHHPHPPIVTPPIIVPIPLPPQKGEHGHHHHHKGSKGPPGPPG 219
                       |.||.....|.:....    ..|.:..:|.||  |..|    |.|:||.||..|
Human   285 -----------PGPPGLAGFPGAKGDQ----GQPGLQGVPGPP--GAVG----HPGAKGEPGSAG 328

  Fly   220 PPG-TGPPGPPGPPGTTYPQPPPPPPPPPPPPPSYPYPPYPYPPPGPYPGPWIPLPVPVPWPSKG 283
            .|| .|.||.||.||.|                                            ..||
Human   329 SPGRAGLPGSPGSPGAT--------------------------------------------GLKG 349

  Fly   284 HKGDKGHKG--GHKGDKGGHHHHYYPPGHDKGGYYPYPPHGGHGGHHHPGHNYPGPYPPPYPPHH 346
            .|||.|.:|  |.||:.|       .||          |.|..|....||  ..||...|.....
Human   350 SKGDTGLQGQQGRKGESG-------VPG----------PAGVKGEQGSPG--LAGPKGAPGQAGQ 395

  Fly   347 PHDGGDKG 354
            ..|.|.||
Human   396 KGDQGVKG 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5225	NP_650587.1	CobT2	<452..>562	CDD:443611
MARCO	NP_006761.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	142..423		99/333 (30%)
		gly_rich_SclB	<147..>396	CDD:468478	95/324 (29%)
		SR	424..519	CDD:214555