DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5225 and dpy-7

DIOPT Version :9

Sequence 1:	NP_650587.1	Gene:	CG5225 / 42053	FlyBaseID:	FBgn0038468	Length:	594	Species:	Drosophila melanogaster
Sequence 2:	NP_509274.1	Gene:	dpy-7 / 181013	WormBaseID:	WBGene00001069	Length:	318	Species:	Caenorhabditis elegans

Alignment Length:	307	Identity:	93/307 - (30%)
Similarity:	104/307 - (33%)	Gaps:	126/307 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    67 QHC------NCPPGPPGPP---GPPGL------PGTPG-------------------PQGPKGHT 97
            |.|      .|||||.|||   |.||:      ||.||                   |.||.|..
Worm    88 QQCTSCVQLRCPPGPIGPPGVSGEPGMDGANGRPGKPGLDGLDVPLDPEPAFPCVICPAGPPGTR 152

  Fly    98 GSKGE---RGEKGERGHYGLPGQPGEPGPIGPPGLPGPPGHKSGHGHHDHHDHHHHHPAPPPPPP 159
            |.:||   .|:.||.||.||||:||:||.:|..|..|.||.:...|
Worm   153 GPQGEVGRPGQTGESGHPGLPGRPGKPGRVGDAGPQGEPGEQGEPG------------------- 198

  Fly   160 PPPPPPPPPPPPHSHPHSHHPHPPIVTPPIIVPIPLPPQKGEHGHHHHHKGSKGPPGPPGPPGTG 224
                                             |..||.....|    ..|.|||||||||  .|
Worm   199 ---------------------------------IKGPPGDDSIG----GTGIKGPPGPPGP--RG 224

  Fly   225 PPGPPGPPGTTYPQPPPPPPPPPPPPPSYPYPPYPYPPPGPYPGPWIPLPVPVPWPSKGHKGDKG 289
            |.||||..|.......||.|.....||.   ||.|...||| |||:            |..||.|
Worm   225 PKGPPGSNGLPSQNSGPPGPIGEMGPPG---PPGPRGEPGP-PGPF------------GPPGDSG 273

  Fly   290 HKGGHKGDKGGHHHHYYPPGHD-----------KGGYYPYPPHGGHG 325
            ..|||.....|......|...:           :|||    ..||:|
Worm   274 EPGGHCPSSCGVQEIVAPSVSELDTNDEPEKPARGGY----SGGGYG 316

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5225	NP_650587.1	None
dpy-7	NP_509274.1	Col_cuticle_N	11..62	CDD:198156
dpy-7	NP_509274.1	Collagen	145..203	CDD:189968	27/109 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000