Protein Alignment Adsl and ADE13

DIOPT Version :10

• Sequence 1: NP_650586.2
• Gene: Adsl / 42051
• FlyBaseID: FBgn0038467
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_013463.1
• Gene: ADE13 / 851073
• SGDID: S000004351
• Length: 482
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 281/481 - (58%)
• Similarity: 362/481 - (75%)
• Gaps: 4/481 - (0%)

  Fly     4 NYEGYKSPLSTRYASKEMQFLFSDQNKFSTWRRLWVWLAKAESRLGLE-ISDAQIAEM--ELQIS 65
            :|:.|.:|||:|||||||...||.:|:|||||:||:.||.||..|||. ::|..|.:|  .::|:
Yeast     3 DYDNYTTPLSSRYASKEMSATFSLRNRFSTWRKLWLNLAIAEKELGLTVVTDEAIEQMRKHVEIT 67

  Fly    66 NIDFEAAAAEERLTRHDVMAHVHVFAKQCPSAAPVIHLGATSCYVGDNTDLIVLRDALKLLLPRV 130
            :.:...|:|:|.:.|||||||||.|.:.||:||.:||||||||:|.||.|||.:|||..:::|::
Yeast    68 DDEIAKASAQEAIVRHDVMAHVHTFGETCPAAAGIIHLGATSCFVTDNADLIFIRDAYDIIIPKL 132

  Fly   131 ASVIARLSQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGVKG 195
            .:||.||::||..|||.|.||:||.|||||||:||||.||||:|:.|.|...|...|:..|||||
Yeast   133 VNVINRLAKFAMEYKDLPVLGWTHFQPAQLTTLGKRATLWIQELLWDLRNFERARNDIGLRGVKG 197

  Fly   196 TTGTQASFLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIHKM 260
            |||||||||.||:|:.:||:.||:.||||.||.|.|.|||||||||:|::::|.|:|...|.|||
Yeast   198 TTGTQASFLALFHGNHDKVEALDERVTELLGFDKVYPVTGQTYSRKIDIDVLAPLSSFAATAHKM 262

  Fly   261 CSDLRILASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLERT 325
            .:|:|:||:.||:|||||.:|||||||.|||||||.||.|:|||||.:|||.|..|.:.||.|||
Yeast   263 ATDIRLLANLKEVEEPFEKSQIGSSAMAYKRNPMRCERVCSLARHLGSLFSDAVQTASVQWFERT 327

  Fly   326 LDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAGGD 390
            |||||.||::|..|||.||..|.||||||.|||||||||||.|..|||||:|||||||||:....
Yeast   328 LDDSAIRRISLPSAFLTADILLSTLLNISSGLVVYPKVIERRIKGELPFMATENIIMAMVEKNAS 392

  Fly   391 RQVCHEKIRVLSQEAGAQVKQHGKDNDLVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGEF 455
            ||..||:|||||.:|.|.||:.|.:|||:.||::|.:|.||.|:||::|:..||.|||..||.:|
Yeast   393 RQEVHERIRVLSHQAAAVVKEEGGENDLIERVKRDEFFKPIWEELDSLLEPSTFVGRAPQQVEKF 457

  Fly   456 VKEEVEPVLARYSEALKNVQDVKLNI 481
            |:::|...|..:.:.| |.:.||||:
Yeast   458 VQKDVNNALQPFQKYL-NDEQVKLNV 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adsl	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	263/437 (60%)
ADE13	NP_013463.1	Adenylsuccinate_lyase_2	11..449	CDD:176471	263/437 (60%)