DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdSL and AT4G18440

DIOPT Version :9

Sequence 1:	NP_650586.2	Gene:	AdSL / 42051	FlyBaseID:	FBgn0038467	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_193579.2	Gene:	AT4G18440 / 827575	AraportID:	AT4G18440	Length:	536	Species:	Arabidopsis thaliana

Alignment Length:	492	Identity:	124/492 - (25%)
Similarity:	194/492 - (39%)	Gaps:	110/492 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 SPLSTRYASKEMQFLFSDQNKFS-TWRRLWV---WLAK----------------AESRL-----G 49
            |||..||.|| ::.|.|..::|. .:.|::|   ||.|                |:|.|     |
plant    83 SPLDGRYWSK-VKDLASSLSEFGLIYFRVFVEIKWLLKLSNIPEVTEVPSFSKEAQSFLQGIIDG 146

  Fly    50 LEISDAQIAEMELQISNIDFEAAAAEERLTRHDVMAHVHVFAKQ-C---PSAAPVI---HLGATS 107
            ..|.||      |:|..|        ||:|.|||.| |..|.|| |   |..|.|:   |...||
plant   147 FSIDDA------LEIKKI--------ERVTNHDVKA-VEYFLKQKCESQPEIAKVLEFFHFACTS 196

  Fly   108 CYVGDNTDLIVLRDAL-KLLLPRVASVIARLSQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWI 171
            ..:.:.:..::|::|| .::||.:..:|..:|..|:::...|.|..||.|||..||:||....:.
plant   197 EDINNLSHALMLQEALSSVILPTMDELIKSISLIAKNFAYVPMLSRTHGQPATPTTLGKEMANFA 261

  Fly   172 QDLIMDERALSRCLEDLRFRGVKGTTGTQASFLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQ 236
            ..|..:.|.||......:|.|..|......|...  |.|...|.  ::.||.|       .:|..
plant   262 VRLSEERRYLSETKIKGKFAGAVGNYNAHISAYS--NIDWPHVS--EEFVTSL-------GLTFN 315

  Fly   237 TYSRKVD-----VEIVAALASLGTTIHKMCSDLRILASRKELEEPFESTQIGSSAMPYKRNPM-- 294
            .|..:::     ..:...::...|.:.....|:....|....::..::.:||||.||:|.||:
plant   316 PYVTQIEPHDYMARLFNNISQFNTILIDFDRDIWSYISLGYFKQTTKAGEIGSSTMPHKVNPIDF 380

  Fly   295 -RSERCCALARHLITLFSSAANTHATQWLERTLDDSA---NRRLTLSEAFLAADAALLTLLNISQ 355
             .||.....|...:|..|...   ....::|.|.||.   |....|..:.||..:|:       |
plant   381 ENSEGNLGKANAELTFLSMKL---PISRMQRDLTDSTVLRNMGGALGHSLLAYKSAI-------Q 435

  Fly   356 GLVVYPKVIERHISQELP---FMSTENIIMAMVKAGGDRQVCHEKIRVLSQEAGAQVKQHGKDND 417
            |:... :|.|..:.::|.   .:..|.|...|.:.|....  :||::.|::  |..|.:
plant   436 GIGKL-QVNEARLKEDLDDNWEVLAEPIQTVMRRYGVPEP--YEKLKELTR--GKAVNE------ 489

  Fly   418 LVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGE 454
                           |.:.|.:........|.||:.|
plant   490 ---------------ETIRTFIKGLELPSEAKDQLLE 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdSL	NP_650586.2	PurB	12..458	CDD:223094	122/490 (25%)
AdSL	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	118/481 (25%)
AT4G18440	NP_193579.2	PLN02848	71..519	CDD:178440	124/492 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	56	1.000	Domainoid score	I4056
eggNOG	1	0.900	-	-		E1_COG0015
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG60641
OrthoDB	1	1.010	-	-		D904932at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3265
orthoMCL	1	0.900	-	-		OOG6_100666
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.730