DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment AdSL and adsl

DIOPT Version :9

Sequence 1:	NP_650586.2	Gene:	AdSL / 42051	FlyBaseID:	FBgn0038467	Length:	481	Species:	Drosophila melanogaster
Sequence 2:	NP_001005457.1	Gene:	adsl / 448055	XenbaseID:	XB-GENE-1001539	Length:	503	Species:	Xenopus tropicalis

Alignment Length:	474	Identity:	324/474 - (68%)
Similarity:	383/474 - (80%)	Gaps:	4/474 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 YKSPLSTRYASKEMQFLFSDQNKFSTWRRLWVWLAKAESRLGLEISDAQIAEMELQISNIDFEAA 72
            |:|||.:||||:||.|.|||..||.||||||:||.:|:..|||.|::.||.|||..:.||||:.|
Frog    32 YRSPLVSRYASREMAFNFSDSKKFQTWRRLWLWLGQAQRSLGLPITEEQIQEMEANLENIDFKMA 96

  Fly    73 AAEERLTRHDVMAHVHVFAKQCPSAAPVIHLGATSCYVGDNTDLIVLRDALKLLLPRVASVIARL 137
            |.||:..|||||||||.||..||.|||||||||||||||||||||||||...||||::|.||:||
Frog    97 AEEEKRLRHDVMAHVHTFAHCCPKAAPVIHLGATSCYVGDNTDLIVLRDGFDLLLPKLARVISRL 161

  Fly   138 SQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGVKGTTGTQAS 202
            :.||:.|.:.|||||||.|||||||||||||||:|||.||.|.|.|...||||||||||||||||
Frog   162 ADFAERYAEMPTLGFTHYQPAQLTTVGKRACLWLQDLCMDLRNLERARNDLRFRGVKGTTGTQAS 226

  Fly   203 FLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIHKMCSDLRIL 267
            |||||:||.:||::||::||..||||:||.|||||||||||||:::.|||||.|:||:|:|:|:|
Frog   227 FLQLFDGDHDKVEELDRMVTSKAGFKRAYIVTGQTYSRKVDVEVLSVLASLGATVHKICTDIRLL 291

  Fly   268 ASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLERTLDDSANR 332
            |:.||||||||..||||||||||||||||||||:|||||:||..:...|.:.||.||||||||||
Frog   292 ANLKELEEPFEKEQIGSSAMPYKRNPMRSERCCSLARHLMTLIMNPLQTASVQWFERTLDDSANR 356

  Fly   333 RLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAGGDRQVCHEK 397
            |:.|:||||.||..|.||.|||:|||||||||||.|.||||||:||||||||||.||:||.|||:
Frog   357 RVCLAEAFLTADIILSTLQNISEGLVVYPKVIERRIRQELPFMATENIIMAMVKNGGNRQDCHER 421

  Fly   398 IRVLSQEAGAQVKQHGKDNDLVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGEFVKEEVEP 462
            ||||||:|.|.|||.|.||||:.|::.|.||:||...|:.:||.|:|||||..||.:|:||||.|
Frog   422 IRVLSQQAAAVVKQEGGDNDLIFRIQSDSYFAPIHAHLEQLLDPKSFTGRAPQQVLKFLKEEVIP 486

  Fly   463 VLARYSEALKNVQDVKLNI 481
            :|:.|...:    |||:.:
Frog   487 LLSPYQSKM----DVKIEL 501

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
AdSL	NP_650586.2	PurB	12..458	CDD:223094	311/445 (70%)
AdSL	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	305/434 (70%)
adsl	NP_001005457.1	Adenylsuccinate_lyase_2	36..471	CDD:176471	305/434 (70%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	319	1.000	Domainoid score	I1241
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H12
Inparanoid	1	1.050	654	1.000	Inparanoid score	I775
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D268338at33208
OrthoFinder	1	1.000	-	-		FOG0004771
OrthoInspector	1	1.000	-	-		oto103686
Panther	1	1.100	-	-	LDO	PTHR43172
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2248
SonicParanoid	1	1.000	-	-		X3924
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	9.190