Protein Alignment Adsl and Fum4

DIOPT Version :10

• Sequence 1: NP_650586.2
• Gene: Adsl / 42051
• FlyBaseID: FBgn0038467
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_723527.1
• Gene: Fum4 / 318995
• FlyBaseID: FBgn0051874
• Length: 484
• Species: Drosophila melanogaster
• Alignment Length: 345
• Identity: 67/345 - (19%)
• Similarity: 125/345 - (36%)
• Gaps: 46/345 - (13%)

  Fly    87 VHVFAKQCPSAAPV-----IHLGATSCYVGDNTDLIVLRDALKL-----LLPRVASVIARLSQFA 141
            :.:...|..|..||     :::..:|    .:|....:|.|:.:     |.|.:.:.|..|.:.:
  Fly   137 IEILGGQMGSKEPVDPNEHVNMAQSS----HDTFSTAVRIAVAMQLQETLYPSLRTFIDLLGKKS 197

  Fly   142 QSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGVKGTT-GTQASFLQ 205
            ..:.|...:|.|||..|...::|:....:.|.|:.....|...:..|....:.||: ||:..
  Fly   198 NDWMDLIKIGRTHLMDAVPLSLGQEFSGYQQQLVNGRTRLDCAMCRLYQLPMGGTSVGTKVD--- 259

  Fly   206 LFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVD-----VEIVAALASLGTTIHKMCSDLR 265
                  .|.:...|.:..:|.......|....:...:.     ||:...|.::..::.|:.:|:|
  Fly   260 ------TKAEYSAQCIKRIAELTFLPFVESPNFFESISACDCLVELHGELNTIAASVMKIANDIR 318

  Fly   266 ILASRK-----ELEEPFESTQIGSSAMPYKRNPMRSE---RCCA--LARHLITLFSSAANTHATQ 320
            .|.|..     ||..|  ..:.|||.||.|.||.:.|   ..||  :..|:......::......
  Fly   319 FLGSGPRCGFGELHLP--ENEPGSSIMPGKVNPTQCEAMSMICAQVMGNHVAVSMGGSSGHFQLN 381

  Fly   321 WLERTLDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMV 385
            .....:..:..|.:|     |..|.......|..:|:......|...:.:.|..::..:..:...
  Fly   382 TFMPMIASNVLRSIT-----LLGDGMKSFCTNCLEGIEPNRSKIGSIVKESLMLVTALSPHIGYE 441

  Fly   386 KAGGDRQVCHEKIRVLSQEA 405
            ::....:..|.....|.|||
  Fly   442 RSAAIAKAAHHNGTTLEQEA 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adsl	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	67/345 (19%)
Fum4	NP_723527.1	Fumarase_classII	24..480	CDD:176465	67/345 (19%)