Protein Alignment Adsl and ade8

DIOPT Version :10

• Sequence 1: NP_650586.2
• Gene: Adsl / 42051
• FlyBaseID: FBgn0038467
• Length: 481
• Species: Drosophila melanogaster
• Sequence 2: NP_596735.1
• Gene: ade8 / 2539985
• PomBaseID: SPBC14F5.09C
• Length: 482
• Species: Schizosaccharomyces pombe
• Alignment Length: 471
• Identity: 266/471 - (56%)
• Similarity: 349/471 - (74%)
• Gaps: 3/471 - (0%)

  Fly     4 NYEGYKSPLSTRYASKEMQFLFSDQNKFSTWRRLWVWLAKAESRLGL-EISDAQIAEME--LQIS 65
            :|..|.:||:.||||.||..|||.:.:.:|||:||:.||.||.:||| :|:|..|.:::  ::|:
pombe     3 DYGSYSTPLTARYASAEMSHLFSREMRINTWRQLWLNLAIAEKQLGLTQITDEAIEQLKAHVKIT 67

  Fly    66 NIDFEAAAAEERLTRHDVMAHVHVFAKQCPSAAPVIHLGATSCYVGDNTDLIVLRDALKLLLPRV 130
            ..:||.||.||:..|||||||::.:....|:|:.:||||||||:|.||.|||.||.|:.||:|::
pombe    68 APEFEIAAKEEKRQRHDVMAHIYTYGLAAPAASGIIHLGATSCFVTDNADLIFLRSAMDLLIPKL 132

  Fly   131 ASVIARLSQFAQSYKDQPTLGFTHLQPAQLTTVGKRACLWIQDLIMDERALSRCLEDLRFRGVKG 195
            .:||.||||::..|||.|||||||.||||||||||||.||||:|:.|.|...|...|:.||||||
pombe   133 VNVINRLSQWSLRYKDIPTLGFTHYQPAQLTTVGKRATLWIQELLWDLRNFVRARNDIGFRGVKG 197

  Fly   196 TTGTQASFLQLFNGDGEKVKQLDQLVTELAGFKKAYAVTGQTYSRKVDVEIVAALASLGTTIHKM 260
            |||||||||.||.||..||::||:||.:|:||...|.||||||.||:|::::..|||.|.|.||:
pombe   198 TTGTQASFLALFEGDHAKVEELDKLVAKLSGFDNVYPVTGQTYDRKIDIDVLQPLASFGATAHKI 262

  Fly   261 CSDLRILASRKELEEPFESTQIGSSAMPYKRNPMRSERCCALARHLITLFSSAANTHATQWLERT 325
            .:|:|:||:.||:|||||:.|||||||.|||||||.||.|:.||:::.|..:|.||.:.||.|||
pombe   263 ATDIRLLANLKEVEEPFEAGQIGSSAMAYKRNPMRCERICSQARYIMNLIPNALNTASVQWFERT 327

  Fly   326 LDDSANRRLTLSEAFLAADAALLTLLNISQGLVVYPKVIERHISQELPFMSTENIIMAMVKAGGD 390
            ||||:|||..|.||||..|:.|..|||:..|:|:|||||::||..|||||:||||||||.|.|..
pombe   328 LDDSSNRRSLLPEAFLFTDSVLKILLNVISGMVIYPKVIQKHIRAELPFMATENIIMAMTKHGAS 392

  Fly   391 RQVCHEKIRVLSQEAGAQVKQHGKDNDLVVRVRKDPYFSPILEQLDTILDAKTFTGRASDQVGEF 455
            |..|||:|||||.:||..||:.|.||||:.|::..|||:||.::||::|||.||.|||.:|...|
pombe   393 RHECHEQIRVLSHQAGRVVKEEGGDNDLIERIKNTPYFAPIYDELDSLLDASTFVGRAPEQTESF 457

  Fly   456 VKEEVEPVLARYSEAL 471
            |.::|...||.:...:
pombe   458 VNKDVSQALAPFKSMI 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Adsl	NP_650586.2	Adenylsuccinate_lyase_2	12..447	CDD:176471	254/437 (58%)
ade8	NP_596735.1	Adenylsuccinate_lyase_2	11..449	CDD:176471	254/437 (58%)