Protein Alignment CG8907 and eps8l3b

DIOPT Version :9

• Sequence 1: NP_001247146.1
• Gene: CG8907 / 42050
• FlyBaseID: FBgn0038466
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_001315008.1
• Gene: eps8l3b / 393332
• ZFINID: ZDB-GENE-040426-1335
• Length: 628
• Species: Danio rerio
• Alignment Length: 725
• Identity: 158/725 - (21%)
• Similarity: 250/725 - (34%)
• Gaps: 219/725 - (30%)

  Fly    47 YALEHLATFKLKNEAEVKQPKEKMKLLVELEKTGGIWPHKMFMSFNGQWLVMLDSDMKEI-ENFP 110
            |.:|||.|..|... ||....:.:..|..|:..|.||...|.:......|.:.|.:.||: |:..
Zfish    51 YRVEHLFTCALDGR-EVSSIDDCVNRLKILDSKGKIWGQDMIIQIQANHLQLCDIETKEVLESVH 114

  Fly   111 GSLITEPTAFISDHPQESFNNILIFSVPGISLGNTEMHIFQVADVSSVLLVEDLK---------- 165
            .:.|.:..|.:...   .::::||.|....|....:..:||..:..:..:..||:
Zfish   115 LNSIRKAKAVLDSC---VYDSLLIISAQEPSQRFPQAFLFQCEEAGAQEVANDLEKSIQQGGDAS 176

  Fly   166 ----------------TLSKGTPVTVDR----NKTPILLPKPERPQNQQAKDQYGIAAAVAGIAA 210
                            .:.:|.|..|.|    |..|...|.|:....:...|.|........:..
Zfish   177 PPIKEPQMDIRSHLESIIGQGYPGNVKRPIQSNPPPPDFPPPQYNSYEDYGDHYDDRRPSPTMQF 241

  Fly   211 EKNAI-------DKEQT-------ERDVQVINHCFEDIERFMARLHYAAEALNELKLRKEQHNPH 261
            .::.:       ::|||       .||::::||...|||.|..::..|....:..|.:|:::.|.
Zfish   242 PRDEVPFRPVQSEREQTPPPFNDVNRDIEILNHVAADIETFTYKVGSALPKDDGSKKKKKKNAPK 306

  Fly   262 GEGLLVLRSRPPIESEFHDILAKAKLALIYSVRLQNQFTKPADP--VHNVFISLKSIVTVCNDIY 324
            ..    :.:.|.:| |:...|.|.|.......:|......|..|  ||::|.||..|::     :
Zfish   307 AP----VANIPTVE-EYVSCLQKIKYGFNILGKLDGHLKNPPAPDFVHSLFSSLGFIMS-----H 361

  Fly   325 VDAGLPQAVLNPLLRRETIAFLNGTLDSNEMQLWQSLGPNWTVPKDQFK--DHKSSYHPIFYDDW 387
            ....:|.:||:|||....:..|...:..||.:||.|||..|.:|:.::.  |....|:|.|||.|
Zfish   362 YPPNIPPSVLSPLLTENALQLLGRVVTPNEDKLWSSLGDAWNIPRSKWPNGDQIPPYYPEFYDGW 426

  Fly   388 SPDWVVDEEVPYLAPALKKSTTPSPVPVPMPPS------PGLGNRTWLSRLESRNVKIAE----- 441
            .|......:.|.....|.:|.:..     .||:      |...||.|    ....:|:||
Zfish   427 QPLPPGPSQSPPANRQLSRSNSER-----FPPANASQRPPEQDNRAW----NPPPMKLAELPLLM 482

  Fly   442 -VTFNKSATNDKELKVTKGEYLEIIDDSRNWWKARNSYGNIGYVPHTVLTPYNFEPGVNGRDTES 505
             |.::..|.|.:||.|.||:.:::||.|..|||.:||....||||..||.|.:
Zfish   483 RVIYDFMARNSQELSVMKGDMVQVIDKSGQWWKVKNSRNEEGYVPQNVLEPVD------------ 535

  Fly   506 LASMALTENGGEEAIPPPLYRNTMAMYTAPVEQPAANGKAMQRTFSMPNVPVPPPMPPPSDSQTP 570
                      ||.                                            ||..:...
Zfish   536 ----------GER--------------------------------------------PPQQNMRG 546

  Fly   571 TPSGTLKRNMAAAGALAAMRARNDCEADDQLYYMQGDVHDELRLLQQQRERRKDLEILKTPEIFI 635
            .||..:|
Zfish   547 PPSLDMK---------------------------------------------------------- 553

  Fly   636 TQNSKPSEVEEWLRGKGFSDIIIKRLHTLSG--------EEIFALSPHTIESYFGRRESRRLISQ 692
               |:|.||:.||:.||||...|:.|..|.|        :||.|:.|......|.:.:|.|....
Zfish   554 ---SRPEEVKAWLQYKGFSKTTIQNLGILDGAMLLRMKRDEIRAICPEEGGRVFFQLQSVRSTVA 615

  Fly   693 IVLQKNFCEY 702
            :..:..|.:|
Zfish   616 LANEAQFSQY 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8907	NP_001247146.1	PTB_EPS8	43..175	CDD:269921	31/154 (20%)
		SH3_Eps8	439..492	CDD:212698	24/58 (41%)
		SAM_superfamily	635..699	CDD:301707	21/71 (30%)
eps8l3b	NP_001315008.1	PTB_EPS8	47..176	CDD:269921	29/128 (23%)
		SH3_Eps8	481..534	CDD:212698	22/52 (42%)
		SAM_superfamily	550..612	CDD:301707	21/122 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586346
Domainoid	1	1.000	65	1.000	Domainoid score	I10016
eggNOG	1	0.900	-	-		E1_KOG3557
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D118943at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12287
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.810