Protein Alignment CG8907 and aru

DIOPT Version :10

• Sequence 1: NP_001247146.1
• Gene: CG8907 / 42050
• FlyBaseID: FBgn0038466
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_722663.1
• Gene: aru / 33268
• FlyBaseID: FBgn0029095
• Length: 805
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 226/700 - (32%)
• Similarity: 303/700 - (43%)
• Gaps: 231/700 - (33%)

  Fly    29 GVPGGNQANGHYD------------------EVKPTYALEHLATFKLKNEAEVKQPKEKMKLLVE 75
            |..||....|.|.                  ..||||.|||||||.:..|:.:..|.:.|:.|::
  Fly    50 GAHGGGGGGGDYSGDDRSGGGEERERLESDLHDKPTYLLEHLATFTVNKESGIVYPADGMRRLLQ 114

  Fly    76 LEKTGGIWPHKMFMSFNGQWLVMLDSDMKE-IENFPGSLITEPTAFISDHPQESFNNILIFSVPG 139
            ||||.|||..||.:..:.||::::|.:... ||.||.||:.|||||.|:...|.:||||:|.|.|
  Fly   115 LEKTTGIWSQKMQLCLDYQWVLIMDYETGNIIERFPASLVQEPTAFTSNDAMELYNNILVFIVSG 179

  Fly   140 ISLGNTEMHIFQVADVSSVLLVEDLKTLSKGTPVTVDRNKTP------------ILLPK------ 186
            .....:||||||...||:|.||||||.|..|..:|..|..||            :::.|
  Fly   180 GGGSRSEMHIFQSQSVSAVHLVEDLKQLRSGKMITQQRGATPTQSGGGGASSMAMMMSKTSSSSS 244

  Fly   187 ----------PERPQNQQAKD------------------QYGIAAAV------------------ 205
                      .:|.:.::.:|                  ||||.|.|
  Fly   245 HSRVELHQHREQRAERERERDRDRERESHHHMHQRSSMEQYGIRAGVGVSGDDVAHISGETDSEH 309

  Fly   206 AGIAA-------EKNAIDKEQTERDVQVINHCFEDIERFMARLHYAAEALNEL----KLRKEQHN 259
            .||..       |.::...|:.||||.|:||||:|||:|:|||.:||.|..||    :.||.:..
  Fly   310 GGIGGGGATERDETSSTSSEKYERDVAVLNHCFDDIEKFIARLQHAAAASRELERRRRNRKSKKR 374

  Fly   260 PHGEGLLVLRSRPPIESEFHDILAKAKLALIYSVRLQNQFTKPADP--VHNVFISLKSIVTVCND 322
            ..|||||.||:|||.|.||.||.||.||:.....:|:.....|..|  ||.:|..|..||...:|
  Fly   375 DPGEGLLTLRTRPPHEKEFVDIFAKFKLSFNLLAKLKAHIHDPNAPELVHFLFTPLALIVEASSD 439

  Fly   323 IYVDAGLPQAVLNPLLRRETIAFLNGTLDSNEMQLWQSLGPNWTVPKDQFKDHKSSYHPIFYDDW 387
            .|.::.||..|:||||.||.|..|...:.|.|.:||:|||..|.:|:||:||...||||:|.|.|
  Fly   440 TYYESQLPARVVNPLLTREAINLLINCVTSKETELWRSLGDAWVIPRDQWKDDVGSYHPVFLDGW 504

  Fly   388 SPDWVVDEEV---PYLAPA-------------------------------------LKKSTT--- 409
            |||:::::|:   |...||                                     ::|.|.
  Fly   505 SPDYLINDELEPPPNSPPAHVSKRRLEVQAGSGLNGRGGGGYDDYDSGNGMNMAMGIEKYTIHHG 569

  Fly   410 ----------------------------------------------------PSPVPV------- 415
                                                                |...|.
  Fly   570 NDGLRERERERDRERAGAISASDFNARSELSFDSIEGRGGGAAGHGHGHGHGPGAGPTLSAITAG 634

  Fly   416 --------------------PMPPSP------GLGN-------RTWLSRLESRNVKIAEVTFNKS 447
                                |.|.|.      ||.|       .:||..|::...||..||:.::
  Fly   635 LQNLHTRESRSGNGYGAGAGPGPSSELGGGGRGLPNVSDDQMLESWLEDLQATGAKIVLVTYPRT 699

  Fly   448 ATNDKELKVTKGEYLEIIDDSRNWWKARNSYGNIGYVPHTVLTPYNFEPG 497
            |.|||||.|.:||||||:||:|.||||||..|.:.:||||::||:||..|
  Fly   700 ANNDKELSVMRGEYLEILDDTRKWWKARNMRGQVAHVPHTIVTPFNFGDG 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8907	NP_001247146.1	PTB_EPS8	43..175	CDD:269921	64/132 (48%)
		SH3_Eps8	439..492	CDD:212698	31/52 (60%)
		SAM_3	630..693	CDD:436214
aru	NP_722663.1	PTB_EPS8	82..215	CDD:269921	64/132 (48%)
		SH3_Eps8	691..744	CDD:212698	31/52 (60%)