DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Irc and ALPHA DOX2

DIOPT Version :9

Sequence 1:	NP_001262653.1	Gene:	Irc / 42049	FlyBaseID:	FBgn0038465	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001185393.1	Gene:	ALPHA DOX2 / 843703	AraportID:	AT1G73680	Length:	640	Species:	Arabidopsis thaliana

Alignment Length:	546	Identity:	118/546 - (21%)
Similarity:	203/546 - (37%)	Gaps:	169/546 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 EGHYAFRRLLGS-SHYRNGF---YQMFPNSGRRETVPAAWSISKELYEPDHIQISKQQTFESNSN 209
            :|.:..|.:..| |.|  ||   |..||.:..::.|.|...::::.:      |.....|    |
plant   102 QGSFIGRNMPPSTSQY--GFFCQYFFFPENLEKKIVVATKLLARKRF------IDNGDQF----N 154

  Fly   210 LALPQWAQFVEHD------------LSKPVSQSMSNGAPIECCSRDQINLQPR-HHHPACAPILY 261
            :....|.||:.||            |..|  :.:::|.|::.....:....|. .||.:.|
plant   155 VIACSWIQFMIHDWVDHLEDTHQIELEAP--EEVASGCPLKSFKFLRTKKVPTDDHHKSGA---- 213

  Fly   262 QPGGKYDVPSCLNYVRSALAVADCNFGGAEQLNQATGSLDLSQLYGFTAAAERKLRVLEGGLLRS 326
                                           :|..|...|.|.:||......|::||.:.|.|:.
plant   214 -------------------------------VNTRTPWWDGSVIYGNDETGMRRVRVFKDGKLKI 247

  Fly   327 TPRG--EFDNALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTIFMRNHNKVAA 389
            :..|  |.|...:||                      :||.|.:.|.|| |:..:|::.||.|..
plant   248 SGDGLLERDERGVPI----------------------SGDIRNSWSGFS-LLQALFVKEHNSVCD 289

  Fly   390 ELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVL-----------------GQKM----- 432
            .||:|.|.:.||||::.|:.|...:..:|...:|..|:|                 |:|:
plant   290 MLKERYPDFDDEKLYRTARLVTAAVIAKVHTIDWTIELLKTDTLTAGMRINWYGFFGKKVKDMVG 354

  Fly   433 -------SSEIRRKQPNR---ALEVSNEFAVAAIRFYFSMLPNELL--NLTKDNVVYGTEKNNQY 485
                   |..:..|:||.   ...::.|| |:..|.: .:||..|:  ::..:||    :|.|.
plant   355 ARFGPLFSGLVGLKKPNDHGVPYSLTEEF-VSVYRMH-CLLPETLILRDMNSENV----DKENP- 412

  Fly   486 VFISKELPTKNLFELKEEIYKPKLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWH-------- 542
             .|.:|:|...|...|......||.:     ..:|.|:.:|....:       .:|:
plant   413 -AIEREIPMTELIGKKAGEKASKLGF-----EQLLVSMGHQSCGAL-------TLWNYPNWMRNL 464

  Fly   543 ------KDTKPTHADILAFDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKT 601
                  .:.:|...|:.|.:|.|.|:.| :|.|......:|..|:..|::.     :|..:.:|.
plant   465 VAQDIDGEDRPHLIDMAALEIYRDRERG-VPRYNEFRKNLLMSPISKWEEL-----TDDEEAIKV 523

  Fly   602 IYASWAD----VDLIVGGISENPVHG 623
            :...:.|    :||.||..:|..:.|
plant   524 LREVYEDDIEKLDLNVGLHAEKKIKG 549

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	117/544 (22%)
Irc	NP_001262653.1	An_peroxidase_like	290..637	CDD:265428	90/388 (23%)
ALPHA DOX2	NP_001185393.1	PLN02283	1..640	CDD:177921	118/546 (22%)
ALPHA DOX2	NP_001185393.1	An_peroxidase	84..609	CDD:281139	118/546 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	109	1.000	Inparanoid score	I2076
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870