Protein Alignment Irc and NOX3

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_056533.1
• Gene: NOX3 / 50508
• HGNCID: 7890
• Length: 568
• Species: Homo sapiens
• Alignment Length: 253
• Identity: 54/253 - (21%)
• Similarity: 87/253 - (34%)
• Gaps: 78/253 - (30%)

  Fly   295 QATGSLDLSQLYGFTAAAERKLRVLEGGLLR---STPR----GEFDNALLPIATDTEGPSFCARA 352
            :|.|....:.|..|.|         ||..|:   |.||    |.|..||    ||......|
Human   354 RAAGDWTAALLEAFGA---------EGQALQEPWSLPRLAVDGPFGTAL----TDVFHYPVC--- 402

  Fly   353 TIGDGTCFAAGDSRVNSSPFSILIYTIFMR-NHNKVAAELKQRNPRW--SDEKLFQAAKAVNVDI 414
                 .|.|||   :..:||:.|:.:|:.: :..:...:|.:....|  .|.:.|
Human   403 -----VCVAAG---IGVTPFAALLKSIWYKCSEAQTPLKLSKVYFYWICRDARAF---------- 449

  Fly   415 YRRVVIEEWLPEVLGQKMSSEIRRKQPNRALEVSNEFAVAAIRFYFSMLPNELLNLT-------- 471
                   ||..::|   :|.|.|..:..:...:|...      |......|:.|::.
Human   450 -------EWFADLL---LSLETRMSEQGKTHFLSYHI------FLTGWDENQALHIALHWDENTD 498

  Fly   472 -----KDNVVYGTEK-NNQYVFISKELPTKNLFELKEEIYKPK-LQYTSQKLNNILES 522
                 |....||... ||::..|:...|:.::...   ...|| |..|.||:.::..|
Human   499 VITGLKQKTFYGRPNWNNEFKQIAYNHPSSSIGVF---FCGPKALSRTLQKMCHLYSS 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	54/253 (21%)
NOX3	NP_056533.1	PLN02844	<67..>426	CDD:215453	26/95 (27%)
		NOX_Duox_like_FAD_NADP	295..568	CDD:99783	54/253 (21%)