DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Irc and CG42331

DIOPT Version :9

Sequence 1:	NP_001262653.1	Gene:	Irc / 42049	FlyBaseID:	FBgn0038465	Length:	697	Species:	Drosophila melanogaster
Sequence 2:	NP_001189281.1	Gene:	CG42331 / 42948	FlyBaseID:	FBgn0259233	Length:	1615	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	149/525 - (28%)
Similarity:	232/525 - (44%)	Gaps:	85/525 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   205 ESNSNLALPQWAQFVEHDLSKPVSQSMSNGAPIECCSRDQINLQPRHHHPACAPILYQPGGKYDV 269
            |:...|.:.||.|.::||::........||:...||.       .:..||||.||.......:..
  Fly   246 EAPLTLMIAQWGQMLDHDMTSTAQPRSINGSIPSCCG-------GKDFHPACFPIKVPLDDPWLA 303

  Fly   270 P---SCLNYVRSALAV-ADCNFGGAEQLNQATGSLDLSQLYGFTAAAERKLRVLEGGLL---RST 327
            |   .||.::|||.|. .||.....||.||.|..:|.|.:|..:|.:....||...|||   |..
  Fly   304 PLKVRCLEFLRSAPAQRRDCVLSWREQTNQVTSYIDASPIYSNSAKSSDNARVFRHGLLVYGRGD 368

  Fly   328 PRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTIFMRNHNKVAAELK 392
            |           |.|.     |.|..|.. .|..:||.|....|..:.::.:::..||::|.||.
  Fly   369 P-----------AEDV-----CQRGAIAT-KCIRSGDGRSGEQPGLLAMHHVWVGEHNRIAMELS 416

  Fly   393 QRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKM----------SSEIRRKQPNRALEV 447
            :.||.|||||::|..:.:...:::.:...|:||.:||:::          |....|........|
  Fly   417 ELNPHWSDEKVYQETRRIVGAMFQHITFREFLPVILGREVVKLFDLELMPSGYYERYSSKVNPTV 481

  Fly   448 SNEFAVAAIRFYFSMLPNELLNLTK-DNVVYGTEKNNQYVFISKELPTKNLFELKEEIYKPKLQY 511
            :|.||.||.||..|::.|......: .||:                  .|...|.||..:..:.
  Fly   482 ANAFAAAAFRFGHSLVQNSYTRCDRHHNVI------------------NNNVSLHEEFQRGDIG- 527

  Fly   512 TSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTH---ADILAFDIQRGRDHGLLPYYRYLE 573
            ::..|:.:|..|.:|..:|.|...:..:..|....|..   .|:.|.:||||||||:.||..:..
  Fly   528 SAGSLHRLLRGLASQRALKRDEFITPELTNHLFQTPGFPFGLDLAAINIQRGRDHGIAPYSAWRV 592

  Fly   574 SCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDLIVGGISENPVHGS-IGPTFSCIISEQF 637
            .|.|| |:.||.||.:.:..:...::...|.|..|:||.||||:|.||.|. :||||:|||::||
  Fly   593 PCGLS-PILSWDDFANVVGPESAKRIGHAYRSVHDIDLFVGGIAERPVVGGLVGPTFACIIAQQF 656

  Fly   638 VHVLK-----------QNQQKAVQKHTELVEQYRHFNGTKLLCLNSGLSAVPQNIFQLPS--ARN 689
            .:..:           ::.....|.|:     .|..:..::||...|...:..:|| :|:  ..|
  Fly   657 SNSRRGDRFWYENGGFESSFTPAQLHS-----LRRVSLAQVLCRTVGGGTLQPHIF-IPAEFEDN 715

  Fly   690 QMVSC 694
            :..:|
  Fly   716 ERQTC 720

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	143/499 (29%)
Irc	NP_001262653.1	An_peroxidase_like	290..637	CDD:265428	110/364 (30%)
CG42331	NP_001189281.1	An_peroxidase	183..699	CDD:281139	143/501 (29%)
CG42331	NP_001189281.1	peroxinectin_like	328..696	CDD:188655	117/409 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	107	1.000	Domainoid score	I2172
eggNOG	1	0.900	-	-		E1_KOG2408
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11475
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920