Protein Alignment Irc and Epx

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_001100507.1
• Gene: Epx / 303414
• RGDID: 1311882
• Length: 715
• Species: Rattus norvegicus
• Alignment Length: 790
• Identity: 197/790 - (24%)
• Similarity: 320/790 - (40%)
• Gaps: 182/790 - (23%)

  Fly     4 IQYICLLAFIIGASLLT-----TIDANSSRDVNAEL-NRIPASKWLQYVETALDSVNR-QKRLED 61
            :|.:..|..::...:||     |:.|..|...|:.| :.|..:|.|  |:||   .|| ||.:..
  Rat     1 MQLLLALLGVLATFILTQLAEGTVPAPPSPVENSVLQDCIAEAKLL--VDTA---YNRTQKSIVQ 60

  Fly    62 NLLGSDITVKNGSLSHAQLLDTL--PSLASKKDNK------LALKILKSSLLVFNSECLPNNIDG 118
            .|       ::||.|...||...  |..|:::..:      :||.:|:..|.  ..|..|.|:..
  Rat    61 RL-------QSGSASPMDLLAYFKQPVAATRRVVQAADYMHVALGLLEEKLQ--PQESRPFNVTD 116

  Fly   119 DKCRSYLEQKPLPEGSSLRTE---CENSLK------GNREGHYAFRRLLGSSHY----------- 163
            ......|.......|.:|:.:   |.|..:      .||.     |..||:|:.
  Rat   117 VLTEPQLRLLSQASGCALQDQVEKCSNKYRTITGRCNNRR-----RPWLGASNQALARWLPAEYE 176

  Fly   164 --------------RNGFYQMFPNSGRRETVPAAWSISKELYE-PDHIQISKQQTFESNSNLALP 213
                          ||||           .:|...::|.::.. |     ||:.|.:...:|...
  Rat   177 DHRSLPFGWTPGKRRNGF-----------LLPLVRAVSNQIVRFP-----SKKLTSDQGRSLMFM 225

  Fly   214 QWAQFVEHDL----SKPVSQSMSNGAPIEC---CSRDQINLQPRHHHPACAPILYQPGGKYDVP- 270
            ||.||::|||    ..|...:.:.|  ::|   |::          .|.|.||...|..    |
  Rat   226 QWGQFIDHDLDFTPESPARVTFNMG--VDCEKTCAQ----------LPPCFPIKIPPND----PR 274

  Fly   271 -----SCLNYVRSALAVADCNFGGAEQLNQATGSLDLSQLYGFTAAAERKLRVLEG--GLLRSTP 328
                 .|:.:.|||.|..........|:|..|..:|.|.:||...:...:||....  |||.:..
  Rat   275 IKSQRDCIPFFRSAPACPQNRNKVRNQINSLTSFVDASMVYGSEVSLALRLRNRTNYLGLLATNQ 339

  Fly   329 RGEFDN--ALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTIFMRNHNKVAAEL 391
            :.: ||  ||||.....|.|.......:.. .||.|||||.:.:|....::|:|:|.||::|.||
  Rat   340 QFQ-DNGRALLPFDNLHEDPCLLTNRLVRI-PCFLAGDSRASETPKLAALHTLFVREHNRLATEL 402

  Fly   392 KQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMSSEIRRK-QPNRAL------EVSN 449
            |:.||.||.:||:..|:.:...:.:.:...::||.|||:   :.:||. .|.|..      .|:|
  Rat   403 KRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGK---ARMRRTLGPYRGYCSNVDPRVAN 464

  Fly   450 EFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFELKEEIYK-------P 507
            .|.: |.||..:||...:..|...   |.|...|.:|.:|..     .|.....:|:       .
  Rat   465 VFTL-AFRFGHTMLQPFMFRLDSQ---YRTSAPNSHVLLSSA-----FFASWRIVYEGGIDPILR 520

  Fly   508 KLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTHADILAFDIQRGRDHGLLPYYRYL 572
            .|..|..|||       .|::|.:|....   ...:..:....|:.|.::||.|||||..|..:.
  Rat   521 GLMATPAKLN-------RQDSMLVDELRD---KLFQQVRRIGLDLAALNMQRSRDHGLPGYNAWR 575

  Fly   573 ESCVLSRPVESWKDFEHFIPS-DVLDKLKTIYASWADVDLIVGGISENPVHGS-IGPTFSCIISE 635
            ..|.||:| .:.......:.: ::..|...:|.:..::|:.||.|:|..:.|: :||..:|:...
  Rat   576 RFCGLSQP-RNLAQLSRVLKNRNLARKFLNLYKTPDNIDIWVGAIAEPLLPGARVGPLLACLFEN 639

  Fly   636 QFVH-------------VLKQNQQKAVQKHTELVEQYRHFNGTKLLCLNSGLSAVPQNIFQLPSA 687
            ||..             |..:.|:||:          |..:.::::|.|:|:|.|.::||:....
  Rat   640 QFRRARDGDRFWWQKWGVFTKRQRKAL----------RRISLSRIVCDNTGISTVSRDIFRANIY 694

  Fly   688 RNQMVSCEDV 697
            ....|||..:
  Rat   695 PQGFVSCSRI 704

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	151/602 (25%)
Epx	NP_001100507.1	myeloperoxidase_like	287..699	CDD:188656	119/446 (27%)