Protein Alignment Irc and Ptgs2

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_058928.3
• Gene: Ptgs2 / 29527
• RGDID: 620349
• Length: 604
• Species: Rattus norvegicus
• Alignment Length: 350
• Identity: 79/350 - (22%)
• Similarity: 137/350 - (39%)
• Gaps: 66/350 - (18%)

  Fly   300 LDLSQLYGFTAAAERKLRVLEGGLLRSTPRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGD 364
            :||:.:||.|...:.|||:.:.|.|:....|  .....|...||: ........:.:...||.|.
  Rat   214 VDLNHVYGETLDRQHKLRLFQDGKLKYQVIG--GEVYPPTVKDTQ-VDMIYPPHVPEHLRFAVGQ 275

  Fly   365 SRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLG 429
            ......|..::..||::|.||:|...|||.:|.|.||:|||.::.:.:....::|||:::..:.|
  Rat   276 EVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWDDERLFQTSRLILIGETIKIVIEDYVQHLSG 340

  Fly   430 Q----KMSSEIRRKQ----PNRALEVSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYV 486
            .    |...|:...|    .||   :::||  ..:..:..:||:
  Rat   341 YHFKLKFDPELLFNQQFQYQNR---IASEF--NTLYHWHPLLPD--------------------- 379

  Fly   487 FISKELPTKNLFELKEEIYKPKLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTHAD 551
                   |.|: |.:|..:|..|...|..|.:.|...:...|.::....:||     ...|....
  Rat   380 -------TFNI-EDQEYTFKQFLYNNSILLEHGLAHFVESFTRQIAGRVAGG-----RNVPIAVQ 431

  Fly   552 ILA---FDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDLIV 613
            .:|   .|..|...:..|..||...|.   :|..|:::...  ..::..:||.:|.....::|..
  Rat   432 AVAKASIDQSREMKYQSLNEYRKRFSL---KPYTSFEELTG--EKEMAAELKALYHDIDAMELYP 491

  Fly   614 GGISENP----VHG----SIGPTFS 630
            ..:.|.|    :.|    .:|..||
  Rat   492 ALLVEKPRPDAIFGETMVELGAPFS 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	78/349 (22%)
Ptgs2	NP_058928.3	EGF	21..53	CDD:394967
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	78/349 (22%)