Protein Alignment Irc and Ptgs2

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_035328.2
• Gene: Ptgs2 / 19225
• MGIID: 97798
• Length: 604
• Species: Mus musculus
• Alignment Length: 326
• Identity: 76/326 - (23%)
• Similarity: 134/326 - (41%)
• Gaps: 65/326 - (19%)

  Fly   300 LDLSQLYGFTAAAERKLRVLEGGLLRSTPRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGD 364
            :||:.:||.|...:.|||:.:.|.|:....|  .....|...||: ........|.:...||.|.
Mouse   214 VDLNHIYGETLDRQHKLRLFKDGKLKYQVIG--GEVYPPTVKDTQ-VEMIYPPHIPENLQFAVGQ 275

  Fly   365 SRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLG 429
            ......|..::..||::|.||:|...|||.:|.|.||:|||.::.:.:....::|||:::..:.|
Mouse   276 EVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSG 340

  Fly   430 Q----KMSSEIRRKQ----PNRALEVSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYV 486
            .    |...|:...|    .||   :::||  ..:..:..:||:..      |:     ::.:|.
Mouse   341 YHFKLKFDPELLFNQQFQYQNR---IASEF--NTLYHWHPLLPDTF------NI-----EDQEYS 389

  Fly   487 FISKELPTKNLFELKEEIYKPKLQYTSQKLNN--ILESLLNQETMKMDAAYSGGVVWHKDTKPTH 549
            |             |:.:|           ||  :||..|.|.........:|.|...::. |..
Mouse   390 F-------------KQFLY-----------NNSILLEHGLTQFVESFTRQIAGRVAGGRNV-PIA 429

  Fly   550 ADILA---FDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDL 611
            ...:|   .|..|...:..|..||...|.   :|..|:::...  ..::..:||.:|   :|:|:
Mouse   430 VQAVAKASIDQSREMKYQSLNEYRKRFSL---KPYTSFEELTG--EKEMAAELKALY---SDIDV 486

  Fly   612 I 612
            :
Mouse   487 M 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	76/326 (23%)
Ptgs2	NP_035328.2	EGF_CA	19..55	CDD:238011
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	76/326 (23%)