Protein Alignment Irc and Ptgs2

DIOPT Version :9

• Sequence 1: NP_001262653.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_035328.2
• Gene: Ptgs2 / 19225
• MGIID: 97798
• Length: 604
• Species: Mus musculus
• Alignment Length: 327
• Identity: 76/327 - (23%)
• Similarity: 133/327 - (40%)
• Gaps: 67/327 - (20%)

  Fly   300 LDLSQLYGFTAAAERKLRVLEGGLLRSTPRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGD 364
            :||:.:||.|...:.|||:.:.|.|:....|  .....|...||: ........|.:...||.|.
Mouse   214 VDLNHIYGETLDRQHKLRLFKDGKLKYQVIG--GEVYPPTVKDTQ-VEMIYPPHIPENLQFAVGQ 275

  Fly   365 SRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLG 429
            ......|..::..||::|.||:|...|||.:|.|.||:|||.::.:.:....::|||:::..:.|
Mouse   276 EVFGLVPGLMMYATIWLREHNRVCDILKQEHPEWGDEQLFQTSRLILIGETIKIVIEDYVQHLSG 340

  Fly   430 Q----KMSSEIRRKQ----PNRALEVSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYV 486
            .    |...|:...|    .||   :::||  ..:..:..:||:..      |:     ::.:|.
Mouse   341 YHFKLKFDPELLFNQQFQYQNR---IASEF--NTLYHWHPLLPDTF------NI-----EDQEYS 389

  Fly   487 FISKELPTKNLFELKEEIYKPKLQYTSQKLNN--ILESLLNQETMKMDAAYSGGVVWHKDTKPTH 549
            |             |:.:|           ||  :||..|.|.........:|.|...::. |..
Mouse   390 F-------------KQFLY-----------NNSILLEHGLTQFVESFTRQIAGRVAGGRNV-PIA 429

  Fly   550 ADILA---FDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFI-PSDVLDKLKTIYASWADVD 610
            ...:|   .|..|...:..|..||...|      ::.:..||... ..::..:||.:|   :|:|
Mouse   430 VQAVAKASIDQSREMKYQSLNEYRKRFS------LKPYTSFEELTGEKEMAAELKALY---SDID 485

  Fly   611 LI 612
            ::
Mouse   486 VM 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	76/327 (23%)
		An_peroxidase_like	290..637	CDD:265428	76/327 (23%)
Ptgs2	NP_035328.2	EGF_CA	19..55	CDD:238011
		prostaglandin_endoperoxide_synthase	75..562	CDD:188648	76/327 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2408
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.78878	Normalized mean entropy	S3904
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.760