Protein Alignment Irc and duox-2

DIOPT Version :9

• Sequence 1: NP_001262653.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_490684.1
• Gene: duox-2 / 186188
• WormBaseID: WBGene00018771
• Length: 1503
• Species: Caenorhabditis elegans
• Alignment Length: 545
• Identity: 137/545 - (25%)
• Similarity: 229/545 - (42%)
• Gaps: 99/545 - (18%)

  Fly   134 SSLRTECE--------NSLKGNREGHYAFRRLL--GSSHYRNGFYQMFPNSGRRETVPAAWSISK 188
            |:|:.|.|        |:| .|.|...|..||.  ..|:|.:|.|.:      ..::|:|..:|.
 Worm    30 SALQQEAETQRYDGWYNNL-ANSEWGSAGSRLHRDARSYYSDGVYSV------NNSLPSARELSD 87

  Fly   189 ELYEPDHIQISKQQTFESNS---NLALPQWAQFVEHDLSKPVSQSMSNGAPIECCSRDQINLQPR 250
            .|:        |.::...|:   ...|..::|.|.:::.:      |||.   .|..:.:.:|.
 Worm    88 ILF--------KGESGIPNTRGCTTLLAFFSQVVAYEIMQ------SNGV---SCPLETLKIQV- 134

  Fly   251 HHHPACAPIL-YQPGGKYDVPSCLNYVRSALAVADCN--FGGAEQLNQATGSLDLSQLYGFTAAA 312
               |.|..:. .:..||..:|    :.|:....|..|  ....||:|:.|..:|.|.:||.|...
 Worm   135 ---PLCDNVFDNECEGKTTIP----FYRAKYDKATGNGLNSPREQINERTSWIDGSFIYGTTQPW 192

  Fly   313 ERKLRVLEGGLLRSTPRG--EFDNALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSIL 375
            ...||..:.|.|.....|  ..:|..:|:  :...|....|....| ..|..||||||.:|..:.
 Worm   193 VSALRSFKQGRLAEGVPGYPPLNNPHIPL--NNPAPPQVHRLMSPD-RLFMLGDSRVNENPGLLS 254

  Fly   376 IYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMS-SEIRRK 439
            ...|..|.||..|.::.:.:|.|:||::||||:.:.:...::::..:::|.:||:.:. |...:.
 Worm   255 FGLILFRWHNYNANQIYREHPDWTDEQIFQAARRLVIASMQKIIAYDFVPGLLGEDVRLSNYTKY 319

  Fly   440 QPNRALEVSNEFAVAAIRFYFSMLPNELLNLTKDN-VVYGTEKNNQYVF-----------ISKEL 492
            .|:....:|:.|..||.||..|::|..:|...:.| ..:.||.......           |.||
 Worm   320 MPHVPPGISHAFGAAAFRFPHSIVPPAMLLRKRGNKCEFRTEVGGYPALRLCQNWWNAQDIVKE- 383

  Fly   493 PTKNLFELKEEIYKPKLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTH---ADILA 554
                 :.:.|.|.....|...:..|.::|.|.:         |..|        |.|   .|::|
 Worm   384 -----YSVDEIILGMASQIAERDDNIVVEDLRD---------YIFG--------PMHFSRLDVVA 426

  Fly   555 FDIQRGRDHGLLPYYRYLESCVLSRPVESWKDF-EHFIPSDV--LDKLKTIY-ASWADVDLIVGG 615
            ..|.||||:|:.||.....:..|:  .::|:.. |.|.....  ::|||.:| .:...:|..|||
 Worm   427 SSIMRGRDNGVPPYNELRRTFGLA--PKTWETMNEDFYKKHTAKVEKLKELYGGNILYLDAYVGG 489

  Fly   616 ISENPVHGSIGPTFSCIISEQFVHV 640
            :.|...:|. |..|..||.:||..:
 Worm   490 MLEGGENGP-GEMFKEIIKDQFTRI 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	129/520 (25%)
		An_peroxidase_like	290..637	CDD:265428	98/368 (27%)
duox-2	NP_490684.1	An_peroxidase	39..552	CDD:281139	133/536 (25%)
		dual_peroxidase_like	41..596	CDD:188652	133/534 (25%)
		FRQ1	792..>895	CDD:227455
		Ferric_reduct	1041..1182	CDD:280043
		NOX_Duox_like_FAD_NADP	1224..1408	CDD:99783

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910