Protein Alignment Irc and skpo-2

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_494540.1
• Gene: skpo-2 / 173686
• WormBaseID: WBGene00015841
• Length: 729
• Species: Caenorhabditis elegans
• Alignment Length: 645
• Identity: 161/645 - (24%)
• Similarity: 273/645 - (42%)
• Gaps: 142/645 - (22%)

  Fly    95 LALKILKSSLLVFNSECLPN----NIDGDKC-----RSYLEQKPLPEGSSLRTECENSLKGNREG 150
            |:::.::.|...||  |.|.    |.:.:.|     ||:       :|:     | |:||....|
 Worm   171 LSIRDVRDSNANFN--CAPTQETPNCNRNLCYHLRYRSF-------DGT-----C-NNLKKPMIG 220

  Fly   151 HYAFRRL--LGSSHYRNGFYQMFPNSGRRETVPAAWSISKELYEPDHIQISKQQTFESNSNLALP 213
            . ||..|  |.:..|.||...  |.|....:.|:|...|:.|       :|.....:.:||..|.
 Worm   221 S-AFTALMRLKNPMYDNGLNA--PTSSFLRSRPSARDASRLL-------LSSSTQIQHHSNALLM 275

  Fly   214 QWAQFVEHDLSKPVSQSMSNGAPIECCSRDQINLQPRHHHPACAPILYQPG----GKYDVPSCLN 274
            ||.||:.|||||   .:|.|......|:.::         ..|..:.....    |::   .||.
 Worm   276 QWGQFIAHDLSK---TTMLNNQECAACTSNK---------GRCTSVFLSRSDPTFGRF---MCLP 325

  Fly   275 YVRSALAVADCNFGGA---EQLNQATGSLDLSQLYGFTAAAERKLRVLEGGLLRSTPRGEFDNAL 336
            ..||...   |..|.:   ||.|:.|..:|.|.:||.:...:...|  :|..|::.   ..:|.:
 Worm   326 VARSTPV---CGTGVSNFREQFNENTAFIDGSMIYGSSDRDQFLFR--QGAFLKTK---LINNRV 382

  Fly   337 LPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDE 401
            .|              .:.......|||.|.|.......::.:::|.||::||.|::.||.|..|
 Worm   383 FP--------------PVDKNNNVVAGDDRANIFVGLASLHVLYLRQHNRIAATLQRVNPHWDQE 433

  Fly   402 KLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMSSEIRR---KQPNRALEVSNEFAVAAIRFYFSML 463
            ::|..::.:...:.:|:...|:||:|||......|..   ..||....|:|||...|.||...|:
 Worm   434 RVFHESRKIVGAMIQRITFTEYLPKVLGVAFEERIGAYPGYDPNIDPSVANEFTSCAFRFGHGMI 498

  Fly   464 PNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFELKEEIYKPKLQYTSQKLNNILESLLN--- 525
                              ...|.|::::..........:.::|     ::..|||.::.|:.
 Worm   499 ------------------QEFYPFLNEKFQHVGGIPFNDGMFK-----STHILNNGIDPLIRGLM 540

  Fly   526 ----QETMKMDAAYSGGVVWHKDTKPTHADILAFDIQRGRDHGLLPYYRYLESCVLSRPVESWKD 586
                :...::..|.:..:.       .::|:.:.:||||||||:.||..:.:.|.|...    ||
 Worm   541 TLPAKMPQRLTPAVTERIF-------GNSDLGSINIQRGRDHGVPPYTVWRKFCGLPEV----KD 594

  Fly   587 FE---HFIPSD-VLDKLKTIYASWADVDLIVGGISENPVHGS-IGPTFSCIISEQFVHVLKQNQQ 646
            ||   ..|.:. |:|.||.:|.....:|:.||.:.|:||..: :|||.||||.|||...  :|..
 Worm   595 FEGLKQVISNQVVIDNLKVVYKHVDAIDMYVGSLLEDPVKDALVGPTLSCIIGEQFKRT--RNGD 657

  Fly   647 KAVQKHT-----ELVEQYRHFNGTKLLCLNSG--LSAVPQNIFQL--PSARNQMVSCEDV 697
            :...:::     |.:.|.:....:::|| ::|  ...||:..|.:  |:|.| :|.|:::
 Worm   658 RLWYENSKVFSPEQLLQIKKITMSRVLC-DAGEHFPMVPRKAFSVFKPTAHN-LVKCDEI 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	139/561 (25%)
skpo-2	NP_494540.1	ShKT	61..95	CDD:214586
		ShKT	101..135	CDD:214586
		An_peroxidase	204..699	CDD:460804	147/591 (25%)