Protein Alignment Irc and Epx

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: NP_031972.2
• Gene: Epx / 13861
• MGIID: 107569
• Length: 716
• Species: Mus musculus
• Alignment Length: 794
• Identity: 196/794 - (24%)
• Similarity: 313/794 - (39%)
• Gaps: 198/794 - (24%)

  Fly     9 LLAFIIG--ASLLTT-------------IDANSSRDVNAELNRIPASKWLQYVETALDSVNRQKR 58
            ||| ::|  |:|:.|             ::.:..||..||...:        |:||.:  :.||.
Mouse     5 LLA-LVGALATLILTQHAEGTAPASPSPVEISVLRDCIAEAKLL--------VDTAYN--HTQKS 58

  Fly    59 LEDNLLGSDITVKNGSLSHAQLLDTL--PSLASKKDNK------LALKILKSSLLVFNSECLPNN 115
            :...|       ::||.|...||...  |..|:::..:      :||.:|:..|....|.  |.|
Mouse    59 IMQRL-------RSGSASPMDLLAYFKQPVAATRRVVQAADYMHVALGLLEERLQPRGSR--PFN 114

  Fly   116 IDGDKCRSYLEQKPLPEGSSLRTE---CENSLKG-----NREGH-------YAFRRLLGSSH--- 162
            .........|.......|.:|:.:   |.|..:.     |.:.|       .|..|.|.:.:
Mouse   115 ATDVLTEPQLRLLSQASGCALQDQAERCSNKYRTITGRCNNKKHPWLGASNQALARWLPAEYEDH 179

  Fly   163 -----------YRNGFYQMFPNSGRRETVPAAWSISKELYE-PDHIQISKQQTFESNSNLALPQW 215
                       .||||           .:|....:|.::.. |     ||:.|.:....|...||
Mouse   180 RSLPFGWTPGKRRNGF-----------LLPLVRDVSNQIVRFP-----SKKLTSDRGRALMFMQW 228

  Fly   216 AQFVEHDL----SKPVSQSMSNGAPIEC---CSRDQINLQPRHHHPACAPILYQPGGKYDVP--- 270
            .||::|||    ..|...:.|.|  ::|   |::          .|.|.||        .:|
Mouse   229 GQFIDHDLDFSPESPARVAFSMG--VDCEKTCAQ----------LPPCFPI--------KIPRND 273

  Fly   271 -------SCLNYVRSALAVADCNFGGAEQLNQATGSLDLSQLYG--FTAAAERKLRVLEGGLLRS 326
                   .|:.:.|||.|..........|:|..|..:|.|.:||  .|.|...:.|....|||.:
Mouse   274 PRIKNQRDCIPFFRSAPACPQNRNKVRNQINALTSFVDASMVYGSEVTLALRLRNRTNFLGLLAT 338

  Fly   327 TPRGEFDN--ALLPIATDTEGPSFCAR--ATIGDGTCFAAGDSRVNSSPFSILIYTIFMRNHNKV 387
            ..|.: ||  ||||.....|.|.....  |.|   .||.|||:|.:.:|....::|:|:|.||::
Mouse   339 NQRFQ-DNGRALLPFDNLHEDPCLLTNRSARI---PCFLAGDTRSSETPKLTALHTLFVREHNRL 399

  Fly   388 AAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMSSEIRRK-QPNRAL------ 445
            ||||::.||.||.:||:..|:.:...:.:.:...::||.|||:   :.|||. .|.|..
Mouse   400 AAELRRLNPHWSGDKLYNEARKIVGAMVQIITYRDFLPLVLGR---ARIRRTLGPYRGYCSNVDP 461

  Fly   446 EVSNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFELKEEIYKP--- 507
            .|:|.|.: |.||..:||...:..|...   |.....|.:|      |..::|.....|...
Mouse   462 RVANVFTL-AFRFGHTMLQPFMFRLDSQ---YRASAPNSHV------PLSSVFFASWRIIHEGGI 516

  Fly   508 -----KLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTHADILAFDIQRGRDHGLLP 567
                 .|..|..|||       .|::|.:|....   ...:..:....|:.|.::||.|||||..
Mouse   517 DPILRGLMATPAKLN-------RQDSMLVDELRD---KLFQQVRRIGLDLAALNMQRSRDHGLPG 571

  Fly   568 YYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDLIVGGISENPVHGS-IGPTFSC 631
            |..:...|.||:|....:........|:..|...:|.:..::|:.||.|:|..:.|: :||..:|
Mouse   572 YNAWRRFCGLSQPRNLAQLSRVLKNQDLARKFLRLYKTPDNIDIWVGAIAEPLLPGARVGPLLAC 636

  Fly   632 IISEQFVH-------------VLKQNQQKAVQKHTELVEQYRHFNGTKLLCLNSGLSAVPQNIFQ 683
            :...||..             |..:.|:||:          |..:.::::|.|:|::.|.::||:
Mouse   637 LFENQFRRARDGDRFWWQKWGVFTKRQRKAL----------RRISLSRIVCDNTGITTVSRDIFR 691

  Fly   684 LPSARNQMVSCEDV 697
            ........|||..:
Mouse   692 ANIYPQGFVSCSRI 705

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	154/604 (25%)
Epx	NP_031972.2	myeloperoxidase_like	288..700	CDD:188656	122/448 (27%)