Protein Alignment Irc and LOC1277631

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_061516638.1
• Gene: LOC1277631 / 1277631
• VectorBaseID: AGAMI1_011985
• Length: 1410
• Species: Anopheles gambiae
• Alignment Length: 747
• Identity: 210/747 - (28%)
• Similarity: 316/747 - (42%)
• Gaps: 135/747 - (18%)

  Fly    33 ELNRIPASKWLQYVETALDSVNRQKRLEDNLLGSDITVKNGSLSHAQLLDTLPSLASKKDNKLAL 97
            |||....|..:...:|.|   |.:||.|     .:..|:.|.:.......|..|.:  |.|:.||
Mosquito   585 ELNMDVISSAINKAKTKL---NERKRQE-----YEAWVRQGGIDAKSPDGTAASFS--KANRNAL 639

  Fly    98 KILKSSLL-------VFNS---------ECLPNNIDG---DKCRSYLEQ-----------KPL-- 130
            .|..:||.       :.||         :...||:.|   |...:.|:.           .|:
Mosquito   640 IIANTSLFYELATNEIVNSLHTLRRRKRQVFDNNLGGFASDDFSNALQSVDVNQFITGSISPINL 704

  Fly   131 -PEGSSLRTECE------------NSLKGNREGH--YAFRRLLGSSHYRNGFYQMFPNSGRRETV 180
             |:..:|...|:            |:|:....|.  ..|.||| ...|.:|..|....|.....:
Mosquito   705 EPQCENLEAPCDTTTPFRTLTAHCNNLRNPELGQSLTVFARLL-PPVYDDGISQPRSLSVTGAPL 768

  Fly   181 PAAWSISKELYEPDHIQISKQQTFESNSNLALPQWAQFVEHDLS-KPVSQSMSNGAPIECCSRDQ 244
            |...||| .|..||   ||...|   ..:|.:.|:|||::|||: .|:.:......| .|.|.|
Mosquito   769 PNPRSIS-SLIHPD---ISNLHT---RYSLMVMQYAQFLDHDLTMTPIHKGFHESIP-SCRSCD- 824

  Fly   245 INLQPRHHHPACAPILYQPGGKY----DVPS----CLNYVRSALAVADCNFGGAEQLNQATGSLD 301
               .||..||.|:|....|...|    :|.|    |...:||  .......|..||:||.|..||
Mosquito   825 ---SPRTVHPECSPFPVPPRDHYYPEVNVTSGERLCFPSMRS--LPGQQTLGPREQINQNTAFLD 884

  Fly   302 LSQLYGFTAAAERKLRVLEGGLLRSTPRGEFDNALL---PIATDTEGPSFCARATIGDGTCFAAG 363
            .||:||......:|||.. .|.|.||........||   |:..:.:.||         |.||.||
Mosquito   885 ASQIYGENGCIAKKLRGF-SGRLNSTIHPIQGKELLPQSPVHPECKSPS---------GYCFIAG 939

  Fly   364 DSRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVL 428
            |.|.:..|....|:|:|||.||::...|:..||.|:.::|::.|:.:.:...:.:...|:||.:|
Mosquito   940 DGRASEQPGLTAIHTVFMREHNRIVEGLRGVNPHWNGDQLYEQARRIVIAQNQHITYNEFLPRIL 1004

  Fly   429 --------GQKMSSEIRRKQPNRALEVS--NEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNN 483
                    |.|:.::...|:.|.....|  .|||.||.|...|:|...:..|:.
Mosquito  1005 SWNAVNLYGLKLLAQGYYKEYNPTCNPSIVTEFATAAFRIGHSLLRPHIPRLSV----------- 1058

  Fly   484 QYVFISKELPTKNLFELKEEIYKPKLQYTSQKLNNILESLLNQETMKMDAAYSGGVVWH--KDTK 546
            |:..|...|..::.|...:...:|.|      ::.|...|:......:|...:|.|..|  :|.:
Mosquito  1059 QHQPIDPPLLLRDGFFRTDNFLQPGL------VDEISRGLVATPMETLDQFITGEVTNHLFEDRR 1117

  Fly   547 PTHA--DILAFDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDVLDKLKTIYASWADV 609
            ...:  |::|.:|.||||||:..|..|...|.|.| .::|:|....||.:|:.:|:.|||...|:
Mosquito  1118 IPFSGFDLIALNIHRGRDHGMPSYNNYRALCNLKR-AQTWEDLGREIPPEVIARLRRIYAHVDDI 1181

  Fly   610 DLIVGGISENPVHGS-IGPTFSCIISEQFVHVLK------QNQQKAVQKHTELVEQYRHFNGTKL 667
            ||..||:||.|:.|. :||||:|||:.||..:.|      :|:...|:...:.:.:.|.....::
Mosquito  1182 DLFPGGMSERPLQGGLVGPTFACIIAIQFRQLRKCDRFWYENEDPVVKFTEQQLAEIRKTTLARI 1246

  Fly   668 LCLNSGLSAVPQN-IFQLPS-ARNQMVSCEDV 697
            :|.|..:....|. .|.||| ..|..|.|..:
Mosquito  1247 ICENLDVGGDMQRAAFDLPSNFLNPRVPCNSM 1278

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	168/566 (30%)
LOC1277631	XP_061516638.1	None