Protein Alignment Irc and LOC11175720

DIOPT Version :10

• Sequence 1: NP_650584.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_061504587.1
• Gene: LOC11175720 / 11175720
• VectorBaseID: AGAMI1_003196
• Length: 715
• Species: Anopheles gambiae
• Alignment Length: 741
• Identity: 146/741 - (19%)
• Similarity: 249/741 - (33%)
• Gaps: 220/741 - (29%)

  Fly    50 LDSVNRQKR----LEDNLLGSDITVK------NGSLSHAQLLDTLPSLASK----KDNKLALKIL 100
            |||:.|:.|    ||  ||.::.||.      :|:....:..:|:....|:    :|.....|:|
Mosquito    85 LDSLERKARRKAILE--LLNNEATVNDPRFLMDGTDFDVRFFNTIAIQPSEQLGVRDTLTTQKVL 147

  Fly   101 KSSLLVFNSECLPNNIDGDKCRSYLEQKPLPEGSSLRTECENSLKGNREGHYAFRRLLGSSHYRN 165
            : .|...:|.|...|:...||.|.:   .|....::...|       .:.||.:|...||.:..:
Mosquito   148 E-VLSKRSSRCQMRNLLDGKCYSNV---TLSCCKAVEEPC-------CDPHYPYRSYDGSCNNLD 201

  Fly   166 GFYQMFPNSGRRETV---PAAWSISKELYEPDHIQISKQQTFESNSNLALPQWAQFV-------- 219
                 .|..|.|.|.   |.|...:..:.:|          ..|.|...|||..:.:
Mosquito   202 -----HPRWGMRGTALKHPIAPCFNDVVSQP----------ARSRSGAPLPQNRKLIAELAVMLK 251

  Fly   220 EHDLSKPVSQSMSNGAPIECCSRDQINLQPR----------------HHH-----PACAPILYQP 263
            |.::|.....:|.:....|..:.|.|....:                |..     |...|:|..|
Mosquito   252 EREISTTAELNMCSVFLSEFFTLDMIGRSTKRTKRRTDGFRGCRADGHDRSPFVTPLSNPLLVSP 316

  Fly   264 GGKYDVP---SCLNYVRSALAVADCNFGGAEQLNQATGSLDLSQLYGFTAAAERKLRVLEGGLLR 325
            ...|..|   .|||:.....|...|........|..:...|||.||...|..::     :|.||.
Mosquito   317 NDPYYGPIGVRCLNFSPQERANDRCELKHMADRNLQSSYFDLSNLYTEQATYDK-----DGKLLL 376

  Fly   326 STPRGEFDNALLPIATDTEGPSFCARATIGDGTCFAAGDSRVNSSPFSILIYTI---FMRNHNKV 387
            .                               .| .|.::..|..|.|:..:.:   |.:.||..
Mosquito   377 Q-------------------------------QC-GAPETITNRRPMSVQFFAVAGLFAKLHNYC 409

  Fly   388 A--AELKQRNPRWSDEKLFQAAKAVNVDIYRRVVIEEWLPEVLGQKMSSEIR---RKQPNRALEV 447
            .  |.||...|      :.:..:|..:.:|::::.|:.|..:.|::..||..   ...|:....|
Mosquito   410 VDRAPLKGSGP------VEERCRAFTIGVYQKIIYEQLLLVLFGEEFYSECDFSCEYNPDEECAV 468

  Fly   448 SNEFAVAAIRFYFSMLPNELLNLTKDNVVYGTEKNNQYVFISKELPTKNLFELKEEIYKP---KL 509
            |..:.....||                         |:|:|.:.:           :|||   :.
Mosquito   469 SQVYKHGPGRF-------------------------QHVWIGETM-----------LYKPARGEA 497

  Fly   510 QYTSQKLNNILESLLNQETMKMDAAYSGGVVWHKDTKPTHADILA-------------------- 554
            ::.|  .|:...   |.|:.....|.:|.:    || |.:...||
Mosquito   498 EWRS--FNDFFH---NYESFDCLGALAGSL----DT-PINVGNLASASVDKFVTVDGYRGTSLPC 552

  Fly   555 FDIQRGRDHGLLP---YYRYLESCV--LSRPVESWKDFEHFIPSDVLDKLKTIYASWADVDLIVG 614
            .|:.|.||.||.|   |..::|...  .||...:::|.......||::.....|....|:|::..
Mosquito   553 IDLARNRDAGLCPLVTYKHHVEQLFGEESRCYSTFEDLSDIFAPDVIEFFSRQYEHPDDIDVLFA 617

  Fly   615 GISENPVHGSIGP----TFSCI------ISEQFVHVLKQNQQKAVQKHTELVEQYRHFNGTKLLC 669
            .:.:....|:..|    ..:|:      .:::|.:....|..:..:   :|:|.   .:.|.||.
Mosquito   618 NMDQRFHPGANLPKMVAQLTCLEMKRLKCTDRFFYTWNPNLGEGAR---QLIEA---MDFTVLLA 676

  Fly   670 LNSGLSAVPQNIFQLPSARNQMVSCE 695
            |.:.:..||...|.:.|.  .:.||:
Mosquito   677 LVTEMEEVPLQPFFVSSP--TVASCD 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_650584.1	An_peroxidase	151..682	CDD:460804	116/611 (19%)
LOC11175720	XP_061504587.1	None