Protein Alignment Irc and tpo

DIOPT Version :9

• Sequence 1: NP_001262653.1
• Gene: Irc / 42049
• FlyBaseID: FBgn0038465
• Length: 697
• Species: Drosophila melanogaster
• Sequence 2: XP_031758614.1
• Gene: tpo / 100036738
• XenbaseID: XB-GENE-920152
• Length: 872
• Species: Xenopus tropicalis
• Alignment Length: 710
• Identity: 176/710 - (24%)
• Similarity: 300/710 - (42%)
• Gaps: 191/710 - (26%)

  Fly   106 VFNSECLP------NNIDGDKCRSYLEQKPLPE-----GSSLR------TEC----------ENS 143
            ||:.:.:|      |:...||  :.|||.|..|     |||..      |.|          .|.
 Frog    33 VFHLDNIPQSALPRNSSQTDK--TSLEQHPESEDVSHTGSSFEAVLANLTGCVPQTLSPFCPNNC 95

  Fly   144 LKGNREGHYAFRRLLGSSHYRNGFYQMFPNSGRRETVPAAWSISKELYEPDHIQISK--QQTFES 206
            |.|.      :|.:.|:.:.||.     |..|...|:.|.|..::  || |.|...|  ::.|..
 Frog    96 LAGK------YRHITGACNNRNN-----PAWGAANTLLARWLPAQ--YE-DGIGEPKGWREEFLY 146

  Fly   207 NSNLALPQ----------------------------WAQFVEHDLS---KPVSQSMSNGAPIECC 240
            | ...|||                            |.|:::||::   :.||::.:.|: ::|.
 Frog   147 N-GFRLPQVREVTNKIIHASSKAFREDDLYSHIIIEWGQYIDHDIAFTPQSVSKTPAIGS-VDCK 209

  Fly   241 SRDQINLQPRHHHPACAPILYQPGGKYDVPSCLNYVRSALAV----ADCNFGG------AEQLNQ 295
            |..: ||.|      |.||............|:.:.||:.|.    ....||.      .||:|.
 Frog   210 STCE-NLYP------CYPIKLSEEDPLSQGGCIPFYRSSSACGTGRGGLKFGNPSLLNPREQING 267

  Fly   296 ATGSLDLSQLYGFTAAAERKLRVL--EGGLLR-STPRGEFDNALLPIATDTEGPSFCARATIGDG 357
            .|..:|.|.:||.:.:.:.||:.|  |.|||| :....:.....||..|    ||.|.:....|.
 Frog   268 LTSFIDASTVYGSSESLQHKLKNLSSEEGLLRVNVKYSDSSREYLPFET----PSACMQDPTADN 328

  Fly   358 T----CFAAGDSRVNSSPFSILIYTIFMRNHNKVAAELKQRNPRWSDEKLFQAAKAVNVDIYRRV 418
            .    ||.||:.|.|.......::|:::|.||::|..||:.||.|:.|..:|.|:.:...:::.:
 Frog   329 AERIDCFFAGEGRANEVITLAAVHTLWLREHNRIAKALKKLNPHWNSETTYQEARKIVGALHQII 393

  Fly   419 VIEEWLPEVLGQKMSSEI--------RRKQPNRALEVSNEFAVAAIRFYFSMLPNELLNLTKDNV 475
            ...:::|::||:....:.        ::..|:    :||.|..||.||..:.:|..:..|
 Frog   394 TFRDYMPKILGKAAYDQYIGLYKGYNQKTNPS----ISNIFTTAAFRFGHATIPPMVHRL----- 449

  Fly   476 VYGTEKNNQYVFISK--ELPTKNLF-----ELKEEIYKPKLQ---YTSQKLNNILESLLNQETMK 530
                  |:|||...|  .||...:|     .:||....|.::   ..|.||...::.:..:.|.|
 Frog   450 ------NSQYVDDPKYPSLPLNEVFFRPWRIVKEGGLDPLIRGLLGKSAKLQTQVDMINEELTEK 508

  Fly   531 MDAAYSGGVVWHKDTKPTHADILAFDIQRGRDHGLLPYYRYLESCVLSRPVESWKDFEHFIPSDV 595
            :....:.|.:          |:.:.::||||||||..|..:.|.|.|||..         .|:|:
 Frog   509 LLVMTNNGSM----------DLASLNLQRGRDHGLPGYNDWREFCGLSRLA---------TPADL 554

  Fly   596 LD---------KLKTIYASWADVDLIVGGISENPVHGS-IGPTFSCIISEQFV------------ 638
            ::         |:..:|:...::|:.:||::|:.:.|: .||.|:|:|.:|..
 Frog   555 INAVSDQKLVAKMIALYSHPDNIDVWLGGLAEDFLPGARTGPLFACLIGKQMQALREGDRFWYEN 619

  Fly   639 -HVLKQNQQKAVQKHTELVEQYRHFNGTKLLCLNSGLSAVPQNIFQLPSARNQMVSCEDV 697
             ::..:.|:..::||:.          ::::|.|:|||.||.:.|.|.:..:..|||:.:
 Frog   620 NNIFTKIQRSELEKHSL----------SRVICDNTGLSHVPLDAFLLGNYPDNFVSCDSI 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Irc	NP_001262653.1	An_peroxidase	151..672	CDD:281139	146/611 (24%)
		An_peroxidase_like	290..637	CDD:265428	101/381 (27%)
tpo	XP_031758614.1	thyroid_peroxidase	116..679	CDD:188657	152/614 (25%)
		CCP	687..736	CDD:153056
		EGF_CA	738..781	CDD:214542

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D276568at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010