DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Sf3a1 and AT1G14650

DIOPT Version :9

Sequence 1:	NP_650583.1	Gene:	Sf3a1 / 42048	FlyBaseID:	FBgn0266917	Length:	784	Species:	Drosophila melanogaster
Sequence 2:	NP_001117289.1	Gene:	AT1G14650 / 838027	AraportID:	AT1G14650	Length:	785	Species:	Arabidopsis thaliana

Alignment Length:	841	Identity:	298/841 - (35%)
Similarity:	418/841 - (49%)	Gaps:	145/841 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DAEANEEQFGNDQPKSMSGP---------IIGIIYPPPEVRNIVDKTASFVARNGPEFEARIRQN 60
            |.|..|.:...:|..|...|         .||||:|||::|.||:|||.||::||.|||.||..:
plant    29 DQEVEERELQAEQNNSNLAPPAAVATHTRTIGIIHPPPDIRTIVEKTAQFVSKNGLEFEKRIIVS 93

  Fly    61 ELGNPKFNFLNGGDPYHAYYRHKVNEFREGNDAGITAL-----ASMKQLAVTSAAQQRQQELLKQ 120
            ...|.|||||...|||||:|:||:.|:|..|..|....     .:..||. |.||.:.:....:.
plant    94 NEKNAKFNFLKSSDPYHAFYQHKLTEYRAQNKDGAQGTDDSDGTTDPQLD-TGAADESEAGDTQP 157

  Fly   121 VVEQQF-VPKE----PPPEFEFIADPPSISALDLDIVKLTAQFVARNGRQFLTNLMSREQRNFQF 180
            .::.|| :|.:    |.||...:..|..|:..:|||:|||||||||||:.|||.|.:||..|.||
plant   158 DLQAQFRIPSKPLEAPEPEKYTVRLPEGITGEELDIIKLTAQFVARNGKSFLTGLSNRENNNPQF 222

  Fly   181 DFLRPQHSLFQYFTKLLEQYTKVLIPPKDLLGKLRSESAPGRSSMNQVLEQVKYRANWQRHQEAQ 245
            .|::|.||:|.:||.|::.|::||:|||||..|||..:|    .:..|||:..:|..|.|.||.|
plant   223 HFMKPTHSMFTFFTSLVDAYSEVLMPPKDLKEKLRKSAA----DLTTVLERCLHRLEWDRSQEQQ 283

  Fly   246 RRREEEKIERERVAYAQIDWHDFVVVETVDYQPFESGNFPPPTNPDEVGAR---VLMEERLMDEE 307
            :::||::.|.|||..|.||||||||||::|:...|....|||...|||..|   ..|||..:.|.
plant   284 KKKEEDEKELERVQMAMIDWHDFVVVESIDFADEEDEELPPPMTLDEVIRRSKASAMEEDEIVEP 348

  Fly   308 GDTEMQIESDDEGDSQANNLLDSGLKLSQMENRVGIQMKNVSSYGQPTGPKRDNTQVQDMDEASS 372
            | .|:::|.|:|    ...|:..|::.:.:|..|.|:  ||                       .
plant   349 G-KEVEMEMDEE----EVKLVAEGMRAANLEENVKIE--NV-----------------------H 383

  Fly   373 DEDTPTTKLQPSVAPMLPPTHDKVVVKKYDPKATQPKQAPMPTD----EYLISPITGEKIPASKV 433
            ||:.|..                 :||.:    .:|:.. :||:    :.:|||||||.||.:::
plant   384 DEEAPMR-----------------IVKNW----KRPEDR-IPTERDPTKVVISPITGELIPINEM 426

  Fly   434 SEHMRIGLLDPRWVEQRDKHTVEKINQDNVFAAGTAIEASLKQLAERRTDIFGVGDEETVIGKKL 498
            ||||||.|:||::.||:|: ...|| ::...|....|..::..||..|.||||..:||.....|
plant   427 SEHMRISLIDPKFKEQKDR-MFAKI-RETTLAQDDEIAKNIVGLARLRPDIFGTTEEEVSNAVK- 488

  Fly   499 GEEETKKDD---RVTWDGHTSSV-EAATRAARANITLEEQIHQIHKVKGLLPDEEK--------E 551
            .|.|.|||:   :|.|||||.|: ..|.:|...|...|||...::......|....        .
plant   489 AEIEKKKDEQPKQVIWDGHTGSIGRTANQALSQNANGEEQGDGVYGDPNSFPGPAALPPPRPGVP 553

  Fly   552 KIGPKPVGNKATLSAP-PQPSTK------------SQHSHSSQSQHHQGGGGGHHGHHNPHHHHP 603
            .:.|.|......|:.| |.||.:            .|..|    |.||....|..||.....:.|
plant   554 IVRPLPPPPNLALNLPRPPPSAQYPGAPRPLGVPMMQPMH----QQHQLTMPGPPGHPQMMMNRP 614

  Fly   604 PHQQ-----APPHQSHHHHPPQQPQPVMQLMQLRPTMMQPPFGAGGGGYMNMQPGGIPQQIAPAP 663
            |..|     .||..|...|..|.|:|..||......|||||          ..||..|    |.|
plant   615 PQMQPGMHVPPPPGSQFAHHMQIPRPYGQLPPSAMGMMQPP----------PMPGMAP----PPP 665

  Fly   664 PVDI---MEEEPPSKKIR-SEDNLIPEADFIATHKSPVTIQVLVPNSDKSEWKLNGQMIAVTM-A 723
            |.:.   :.|||.:|:.: .|..|:||..|:|.|..|.||:|..||.:      :||.:.:|: :
plant   666 PEEAPPPLPEEPEAKRQKFDESALVPEDQFLAQHPGPATIRVSKPNEN------DGQFMEITVQS 724

  Fly   724 LSEPIANLKTKLQDETGMPPAKQKIFYEGMFFKDSNTMAFYNLVNGTTVHLQVKERGGRKK 784
            |||.:.:||.|:..|..:|..|||:..:..|.||:.::|.||:..|..:.|.::||||||:
plant   725 LSENVGSLKEKIAGEIQIPANKQKLSGKAGFLKDNMSLAHYNVGAGEILTLSLRERGGRKR 785

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Sf3a1	NP_650583.1	SWAP	36..89	CDD:197818	30/52 (58%)
		Surp	150..200	CDD:280053	30/49 (61%)
		PRP21_like_P	227..479	CDD:289034	85/258 (33%)
		SF3a120_C	709..784	CDD:176395	27/75 (36%)
		UBQ	713..777	CDD:214563	22/64 (34%)
AT1G14650	NP_001117289.1	SWAP	69..121	CDD:197818	30/51 (59%)
		SWAP	191..244	CDD:197818	32/52 (62%)
		PRP21_like_P	262..470	CDD:403444	85/261 (33%)
		PAT1	<540..>643	CDD:401645	26/106 (25%)
		Ubl_SF3a120	702..778	CDD:340498	28/81 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	112	1.000	Domainoid score	I2065
eggNOG	1	0.900	-	-		E1_KOG0007
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	396	1.000	Inparanoid score	I482
OMA	1	1.010	-	-		QHG55212
OrthoDB	1	1.010	-	-		D1256232at2759
OrthoFinder	1	1.000	-	-		FOG0003484
OrthoInspector	1	1.000	-	-		otm2971
orthoMCL	1	0.900	-	-		OOG6_102246
Panther	1	1.100	-	-	LDO	PTHR15316
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3377
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.840