DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3534 and rhaB

DIOPT Version :9

Sequence 1:	NP_650582.1	Gene:	CG3534 / 42047	FlyBaseID:	FBgn0038463	Length:	552	Species:	Drosophila melanogaster
Sequence 2:	NP_418340.1	Gene:	rhaB / 948399	ECOCYCID:	EG11868	Length:	489	Species:	Escherichia coli

Alignment Length:	501	Identity:	97/501 - (19%)
Similarity:	161/501 - (32%)	Gaps:	134/501 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 SGSGQQHGSLYWSKHGINTLQNLDSEKFLHAQI-----------------DDSAFVVNRTPIWMD 141
            :|...|:|.:.|....:.:...|...|.....|                 |.....|.....:.|
E. coli    40 NGLHSQNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRD 104

  Fly   142 ATTTKQCLEMEMAVGGKLNMVELTGSKCYERFTGPQIRKIYQQRCHAYEEANRISLVSSFISSLF 206
            :.|.....:.:..: ||.::.:.:|.:.....|..|:|.:.:|:...........|:..:.|...
E. coli   105 SRTNGLMAQAQQQL-GKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLMPDYFSYRL 168

  Fly   207 LGSVAPIDFSDGSGMNLLDIRKKNW------SKECLNVCAPDLDKRL-----------DIPVSPN 254
            .|                   |.||      :.:.:|:.:.|.|:.|           ..|..|.
E. coli   169 TG-------------------KMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPG 214

  Fly   255 SIL-------GNVSPYFVERFSFSPDCKVAASTGDNPSA-LSGMLVGSSWLTISMGTSDTLMMSL 311
            :::       ||..|.            ||.::.|..|| ::..|.||....:|.||...:....
E. coli   215 NVIGHWICPQGNEIPV------------VAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFES 267

  Fly   312 KEPLN---------WEEGHILCHPTETEEFMGLLCFRNASLVREEMNKKTTGGDWDKFNEYLDST 367
            :.|..         ..||.........:..|||...:.. |..:::|      |.........:.
E. coli   268 QTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRV-LQEQQIN------DLPALISATQAL 325

  Fly   368 PRGNFGNMAVHFNDMEII------PKAQGILRWNREMDPSSPDAARGVIKFSSPQIEIRALVEGQ 426
            |...|   .::.||...|      .:.|...|...:..|.| ||......|.|     .||:...
E. coli   326 PACRF---IINPNDDRFINPETMCSEIQAACRETAQPIPES-DAELARCIFDS-----LALLYAD 381

  Fly   427 MLHHRAVAEDLGYKFGPETQILVTGGASVNKSILQTIAD-----VFNAPVHIQDEGFEAALLGAA 486
            :||.  :|:..|..|   :|:.:.||...|..:.|..||     |...||       ||:.||..
E. coli   382 VLHE--LAQLRGEDF---SQLHIVGGGCQNTLLNQLCADACGIRVIAGPV-------EASTLGNI 434

  Fly   487 YRSAYALYLQEAGDGVTPLCYRDY--ILSLTSNKLSLVCEPHKDSE 530
              ....:.|.|..:      ..|:  ::|.|:|..:..  |:.|||
E. coli   435 --GIQLMTLDELNN------VDDFRQVVSTTANLTTFT--PNPDSE 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3534	NP_650582.1	FGGY_D-XK_euk	10..491	CDD:212660	87/458 (19%)
		PLN02669	11..546	CDD:178274	97/501 (19%)
		NBD_sugar-kinase_HSP70_actin	<447..545	CDD:302596	23/91 (25%)
rhaB	NP_418340.1	rhaB	19..489	CDD:182609	97/501 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1070
Hieranoid	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10196
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	3	2.910